Objective To investigate the value of ultrasonic diagnosis on vascular injury after femoral vein catheterization in patients with liver failure undergoing artificial liver support therapy. Methods Clinical features and ultrasonic changes of vascular injury after femoral vein catheterization in patients with liver failure undergoing artificial liver support therapy from January 2013 to November 2018 in our hospital were analyzed retrospectively. Results 16 liver failure patients complicated with vascular injury, including 12 cases of localized intramuscular hematoma (75.00%), 2 cases of intramuscular hematoma with retroperitoneal hematoma (12.50%), and 2 cases of pseudoaneurysm (12.50%). Conclusions