超声和荧光素眼底血管造影在葡萄膜转移癌诊断中的价值研究
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四川省绵阳市中心医院超声科

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Ultrasound and fluorescein fundus angiography in the diagnosis of metastases of cancer to uveitis research value
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1.Ultrasonic department;2.Mianyang Central Hospital of Sichuan 621000

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    目的:研究葡萄膜转移癌的超声和荧光素眼底血管造影的影像学特点并分析其诊断价值。方法:回顾性分析2014年1月1日至2019年2月1日我院收治的25例葡萄膜转移癌患者的临床资料,其中21例23只眼为脉络膜转移癌,4例5只眼为虹膜转移癌。25例患者均常规检查视力、散瞳、眼压、眼底,行腹部B超和胸部CT;另外行B型超声或(和)彩色多普勒超声检查21例23只眼,荧光素眼底血管造影检查17例19只眼,UBM检查4例5只眼,分析患者的临床特征和影像学特点。结果:25例28只眼中,B超检查脉络膜转移癌21例23只眼,可见视盘周围、眼球后极部或颞上方实质性占位病变,呈现扁平、半球形或不规则波浪形隆起的回声光团;FFA检查脉络膜转移癌17例19只眼,早期表现为无脉络膜背景萤光的暗部,动静脉期呈斑点状荧光或斑片状强荧光,静脉期呈高荧光斑点。晚期呈高斑驳状荧光;UBM检查虹膜转移癌4例5只眼,可见虹膜内瞳孔缘存在实性隆起、回声较均匀的肿物,虹膜根部厚度增加。结论:葡萄膜转移癌多以脉络膜转移癌最为多见,多发生于单个眼单个病灶,B超或彩超检查颞上方或极部不规则实质性占位,基底血流丰富;荧光素眼底血管造影早期萤光较低,中期呈现点状或斑片状高荧光,晚期呈斑驳状持续高萤光。

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    Objective: To study the uveal metastases ultrasound and fluorescein angiography imaging characteristics and to analyze its diagnostic value. Methods: A retrospective analysis of patients with metastatic uveal clinical data of 25 cases of January 1, 2014 to February 1, 2019 in our hospital, 21 cases 23 eyes with choroidal metastases, 4 5 iris metastasis cancer. 25 patients were routinely check vision, mydriasis, intraocular pressure, eyes, abdominal B ultrasound and chest CT; additional line B-mode ultrasound or (and) color Doppler ultrasound 21 cases 23 eyes, fundus fluorescein angiography check the 17 cases 19 eyes, UBM examination 4 cases 5 eyes, analyzed the clinical manifestations characteristic imaging features. Results: 25 cases 28 eyes, B-ultrasound choroidal metastases 21 cases 23 eyes, seen around the optic disc, rear pole of the eye or above the substantial temporal lesions, showing a flat, hemispherical or irregular wavy raised back sound and light group; FFA examination choroidal metastases 17 cases 19 eyes, an early manifestation of weak fluorescence, arteriovenous phase in spots or patchy fluorescence intensity fluorescence, was intravenously of highly fluorescent spots. Late mottled fluorescence was high; UBM examination 4 cases of metastatic cancer five iris eye, visible within the iris pupil margin exists a real uplift, uneven echo mass, iris thickness increases. Conclusion: uveal metastases mostly choroidal metastases is the most common, occurs in a single eye single lesions, B-ultrasonography or above the temporal or substantive pole irregular mass, rich basal blood; fundus fluorescein angiography early fluorescent low, mid presented punctate or patchy high fluorescence late mottled sustained high fluorescence.

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熊敏,郭道宁.超声和荧光素眼底血管造影在葡萄膜转移癌诊断中的价值研究[J].临床超声医学杂志,2019,21(11):

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  • 收稿日期:2019-03-20
  • 最后修改日期:2019-03-20
  • 录用日期:2019-03-26
  • 在线发布日期: 2019-11-26
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