| 摘要: |
| 目的 探讨强直性脊柱炎（AS）患者骶髂关节超声与CT、MRI图像融合的方法及其可行性。方法 对84例AS患者（病例组）和30例正常成人（对照组）的骶髂关节进行超声与CT、MRI图像融合。图像融合操作分别在骶髂关节第一至第三骶后孔横截面（level）进行，统计并比较两种融合形式在两组3个level下的融合成功率。分析骶髂关节的不同层面、背侧骶骨区皮脂厚度及患者骶髂关节的病变程度与融合成功率的关系。结果 病例组和对照组超声与CT图像在各level层面的融合成功率均＞85%，组间比较差异均无统计学意义，组内各level层面之间比较，差异均无统计学意义；病例组和对照组超声与MRI T1WI、T2WI图像在各level层面的融合成功率均＜50%，组间比较差异均无统计学意义。病例组各level层面中4个Class之间的融合成功率比较，差异均无无统计学意义（P=0.136、0.708、0.311）。两组各level层面的融合成功与融合失败者间背侧骶部皮脂厚度比较，差异均有统计学意义（均 P＜0.05）。结论 建立骶髂关节超声与CT图像融合成像的方法并证实其可行性，为融合图像联合多普勒超声评估骶髂关节后部异常血流信号提供了技术基础。背侧皮脂厚度是影响图像融合成功率的主要因素。 |
| 关键词: 超声检查 CT MRI 图像融合 强直性脊柱炎 骶髂关节 |
| DOI： |
| 投稿时间：2019-03-26修订日期：2019-06-16 |
| 基金项目:国家自然科学基金面上项目(81571684) |
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| Methodology and feasibility study of US-CT/US-MRI image fusion in sacroiliac joints of ankylosing spondylitis patients |
| HU Zhenlong,ZHU Jiaan |
| (Department of Medical Ultrasound,Shanghai General Hospital,Shanghai JiaoTong University,School of Medicine) |
| Abstract: |
| Objective In this study，we aimed to verify the methodology and feasibility of fusion imaging of the sacroiliac joints （SIJ） of ankylosing spondylitis （AS） patients. Methods We performed ultrasound（US）-CT and US-MRI fusion imaging of SIJs with 84 inpatients and 30 controls to compare the fusion success rates at 3 cross-sectional levels of the posterior sacral foramina （level1-3，respectively）. Possible factors impacting the fusion success rate were considered and analyzed including the lesion classes of SIJ，the skin fold thickness of the sacral region and the morphological difference of 3 SIJ levels.Results Data showed high success rates of image fusion of US-CT at the 3 levels in both the patient group and the control group.However，no significant differences were observed between the groups at the 3 levels （all P＞0.05）；Success rates of image fusion of US-MRIT1WI and US-MRIT2WI in patient group at the 3 levels were lower than 50%，no significant differences were observed between the two groups at the 3 levels （all P＞0.05）.In the cases of US-CT image fusion，the differences in the imaging success rates between the 4 classes of SIJ lesions were not significant at any level （P=0.136，P=0.708，and P=0.311）.Furthermore，a difference in the mean skinfold thickness at each of the 3 SIJ levels was observed between the successful and failed cases in both the patients’ and control group.Conclusion We established the methodology of fusion imaging of the SIJ.It is suggested that US-CT fusion imaging is feasible with SIJs of AS patients；the skinfold thickness was identified as the main factor affecting the success rates. |
| Key words: Ultrasonography,CT,MRI,Fusion Imaging,Ankylosing Spondylitis,sacroiliac joint |
