Objective: To investigate the correlation between multimode ultrasonography features and pathological basis of cervical lymph node tuberculosis. Methods: From January 2017 to March 2019, 105 patients in our hospital were selected. Multimode ultrasonography was performed before lymph node biopsy. According to the pathological results, the patients were divided into tuberculosis group and non-tuberculosis group. Multimode ultrasound findings were compared between the two groups. Logistic multivariate regression was used to analyze the related factors of lymph node tuberculosis. Results: 37 cases (52.86%) in tuberculosis group had clear lymph node boundary, 53 cases (75.71%) had disappeared echogenic hilus, 54 cases (77.14%) had elastography score <2, 42 cases (60.00%) had elastic strain ratio <2, 56 cases (80.00%) had liquefaction necrosis, which was significantly higher than that in non-tuberculosis group (P< 0.05).Logistic multivariate regression analysis showed that liquefaction necrosis, clear boundary of lymph node and elastography score < 2 were independent correlative factors of lymph node tuberculosis. Conclusion: Liquefied necrosis, clear boundary of lymph nodes and elastographic score < 2 are related to cervical lymph node tuberculosis. Multi-mode ultrasonographic findings is helpful for the diagnosis of cervical lymph node tuberculosis.