| 摘要: |
| 摘要：目的：探讨超微血流成像（SMI）及能量多普勒超声（PDUS）在类风湿关节炎（RA）临床缓解期的应用价值。方法：对40例RA临床缓解期患者和20例健康志愿者的双侧腕关节、掌指关节及近端指指关节进行超声检查，记录PDUS及SMI对增厚滑膜内血流分级结果，观察两种血流模式对滑膜血流的显示率和滑膜血流分级的差异。 结果:在40例RA临床缓解期患者中，PDUS和SMI显示的缓解率分别为60%和27.5%，两者的差异有统计学意义（P<0.05）；在20例健康志愿者中SMI和PDUS对滑膜血流的显示率为0，但在40例RA临床缓解期患者中，PDUS及SMI对滑膜血流的显示率分别为8.64%、12.8%，两种血流模式的血流信号显示率差异具有统计学意义（P<0.05）；PDUS与SMI对滑膜血流分级结果一致性较好（kappa=0.741）； SMI阳性患者继续强化治疗后，滑膜血流显示率明显下降。结论：在类风湿关节炎临床缓解期，SMI和PDUS都有一定的临床应用价值。但SMI比PDUS能够更敏感的发现手腕关节滑膜中的血流信号。 |
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| DOI： |
| 投稿时间：2019-04-15修订日期：2019-05-11 |
| 基金项目:洛阳市科技计划医疗卫生项目(1603001A-10)作者单位：471003 洛阳市,河南科技大学第一附属医院超声医学科通讯作者：张周龙,Email：346643661@qq.com 张周龙 吕海霞 姚俊东 |
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| The Application of Superb Micro-vascular Imaging and Power Doppler Ultrasound in Rheumatoid Arthritis in clinical remission |
| PENG Jinjin,ZHANG Zhoulong |
| (Department of Ultrasound,the First Affiliated Hospital of Henan University of Science and Technology) |
| Abstract: |
| Abstract: Objective To investigate the application value of Superb micro-vascular imaging(SMI) and Power Doppler ultrasound(PDUS) in Finger and Wrist Joints with Rheumatoid Arthritis in clinical remission. Methods The bilateral wrist, metacarpophalangeal joint and proximal phalangeal joint of 40 clinical remission patients and 20 healthy volunteers were examined by ultrasound. The blood flow grading results of PDUS and SMI on thickened synovial membrane were recorded. To observe the difference between the two blood flow patterns in the display rate of synovial blood flow and the classification of synovial blood flow. Results In the 40 patients with RA in clinical remission,the remission rates of PDUS and SMI were 60% and 27.5%, respectively. There was significant difference between the two groups (P < 0.05); In the 20 healthy volunteers,the detection rate of synovial blood flow by SMI and PDUS was 0. However, In the 40 patients with RA clinical remission, the synovial blood flow display rates of PDUS and SMI were 8.64% and 12.8%,respectively,The difference of blood flow signal display rate between the two blood flow patterns was statistically significant(P < 0.05); The results of synovial blood flow grading by PDUS and SMI were consistent (kappa=0.752);after intensive treatment of SMI positive patients, the rate of synovial blood flow display decreased significantly. Conclusion In the clinical remission stage of rheumatoid arthritis. SMI and PDUS have certain clinical application value , but SMI is more sensitive than PDUS in detecting the blood flow signal in the synovial membrane of finger and wrist joints. |
| Key words: Rheumatoid arthritis Clinical Remission Superb micro-vascular imaging Power Doppler ultrasound |
