| 摘要: |
| 目的 应用超声剪切波频散技术（SWD）检测颈动脉粘弹性，初步探讨其对动脉机械特性的影响。方法 招募健康志愿者45例，依据年龄中位数分为高年龄组（≥50岁）和低年龄组（＜50岁）。采用SWD检测受试者颈总动脉粘弹性，获取颈动脉弹性模量（SWER）和粘性指标（SWDR），及左右侧颈动脉最大和平均环壁张应力（L-PTS、L-MTS、R-PTS和R-MTS）。采用Pearson相关分别分析SWER和SWDR与L-PTS、L-MTS、R-PTS及R-MTS的相关性。结果 ①与低年龄组比较，高年龄组受试者颈总动脉SWER和SWDR均减小（P＜0.05）。②高年龄组受试者R-PTS较低年龄组者小（P＜0.05）。③SWER与R-PTS、R- MTS、L-PTS和L-MTS呈正相关（r=0.218、r=0.359、r=0.209和r=0.369，P均＜0.05）。SWDR与R-PTS、R- MTS、L-PTS和L-MTS不相关（P＞0.05）。结论 颈总动脉环壁张应力与其弹性指标相关，而与其粘性指标不相关，该结果有望为研究动脉壁机械特性提供一个新的视角。 |
| 关键词: 剪切波频散 颈动脉 粘弹性 环壁张应力 |
| DOI： |
| 投稿时间：2019-04-28修订日期：2019-05-15 |
| 基金项目: |
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| Carotid elasticity determinates its mechanical properties: a preliminary study |
| Luo Xianghong,Li Zhaojun |
| (Shanghai General Hospital, Shanghai Jiaotong University School of Medicine) |
| Abstract: |
| Objective To detect the carotid viscoelasticity and the relationship of mechanical properties and viscoelasticity using shear wave dispersion (SWD) technique. Methods Forty-five volunteers were recruited and divided into the older group (≥50 years old) and the younger group (<50 years old) according to the median age. The carotid arteries were examined by SWD and the indicators were obtained, including the carotid elastic modulus (SWER) and viscous index (SWDR), as well as the maximum and average tensile stress of the left and right carotid arteries (L-PTS, L-MTS, R -PTS and R-MTS). The correlations between SWER, SWDR and tensile stress were analyzed by Pearson analysis, respectively. Results ① In the older group, the carotid SWER and SWDR were lower than those in the younger group (P<0.05). ② The R-PTS was also lower in the older group (P<0.05). ③ SWER was positively correlated with R-PTS, R-MTS, L-PTS and L-MTS, respectively (r=0.218, r=0.359, r=0.209 and r=0.369, all P<0.05). SWDR was not significantly associated with R-PTS, R-MTS, L-PTS and L-MTS, respectively (P>0.05). Conclusion The carotid tensile stress was related to its elasticity but not related to its viscosity. It could be a new perspective for studying the mechanical properties of the arterial wall. |
| Key words: Shear wave dispersion Carotid artery Viscoelasticity Tensile stress |
