Objective To explore the clinical application of bedside color Doppler ultrasound guided inferior vena cava filter implantation in the ward patient for the prevention of pulmonary embolism after deep vein thrombosis. Methods Twenty-eight patients in the ICU or ward who had the deep vein thrombosis of the lower extremities were operated bedside by the vascular surgeon from October 2016 to October 2018. Results All the cases were successful. The operation time was 20～35 min and the average time was 30 min. The whole periods were guided by the ultrasound on real time, Before the operation, the ultrasound doctor assessed the inferior vena cava patency by the color Doppler ultrasound. During the procedure, the doctor had taken the accurate puncture path and guidance of the whole implantation operation. After the operation, the ultrasound doctor made the examination for the filter which location and patency. No complications of vascular related were found after surgery. Conclusion Bedside color Doppler ultrasound guided inferior vena cava filter implantation was simple ,safe, convenient and fast, this way especially for the patient in the ICU or ward who could not be moved. It would avoided the radiation of the X-ray through the conventional operation way to the doctor and patient. This method could not only made operate accurately and reduced the vascular complication effectively, but also was helpful to the clinical treatment and prevent the pulmonary embolism.