Objective To explore the application and value of active learning strategies for remolding the traditional lecturing teaching. Methods Sixty medical imaging undergraduates in Chongqing Medical University were randomly divided into two groups (trail group and control group). A designed active learning strategy was used in the lectures of the trial group, while the control group were applied the unchanged traditional teaching. Questionnaire and test were used to analyze the practicality of students'' knowledge acquisition and their recognition for the active learning teaching. Results For the improved teaching methodology, the number of students thought that it was helpful to the understanding in class was 27(90%), and that it was conductive to concentration and duration was 25(83.33%), there were 25(83.33%) students agreed it would help to review, and 6(20%) students had felt burdened in modified lectures, and 24(80%) students considered the improved lectures could go on. Test result showed that the mean score of trail group was statistically higher than that of control group(83.5±7.5 vs 71.7±10.4，P＜0.05),and the pass rate of trial group was significantly higher than that of control group(86.67% vs 63.33%，P＜0.05). Conclusion The active learning strategy is benefit to teaching effect in ultrasound diagnostics, deserving extensive application in future.