| 摘要: |
| 目的 探讨三维斑点追踪超声心动图(three-dimensional speckle tracking echocardiography,3D-STE)在评价高尿酸血症患者左心室功能中的价值。方法 纳入40例健康对照者和80例高尿酸血症患者,采集并分析3D-STE检查。比较高尿酸血症患者和健康对照组的实验室检查结果和3D-STE参数,包括卒中容积(stroke volume,SV)、整体纵向应变(global longitudinal strain,GLS)和整体圆周应变(global circumferential strain ,GCS)。结果 高尿酸血症患者与健康对照之间在体质指数(24.70?±?2.9 vs. 21.83?±?2.4 kg/m2, P?=?0.001)、C反应蛋白 (5.82?±?9.4 vs. 1.12?±?1.8, P?=?0.012)、谷丙转氨酶 (34.26?±?26.6 vs. 17.60?±?13.0, P?=?0.011)、谷草转氨酶(24.90?±?11.3 vs. 17.70?±?4.1, P?=?0.001)、尿素氮(5.11±1.6,vs. 4.18±0.6 mmol/L,P＝0.046)、肌酐(90.25±14.6)vs 77.93±10.8μmol/L,P＝0.006)和肾小球滤过率(87.87±0.006比α±mL/min /1.73m2,P＝0.001)有显著统计学差异。高尿酸血症患者3D-STE检查中SV (54.71?±?9.6 vs. 61.92?±?14.4 mL, P=?0.024), GLS (??20.51?±?4.0 vs. ??23.20?±?4.0%, P?=?0.019), and GCS (??31.30?±?5.0 vs. ??35.65?±?2.5%, P
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| 关键词: 三维斑点追踪超声心动图 高尿酸血症 左心室功能 |
| DOI： |
| 投稿时间：2019-06-04修订日期：2019-08-15 |
| 基金项目:江苏省卫生计生委2016年度面上科研课题（H201610） |
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| The value of three-dimensional speckle tracking echocardiography in evaluating left ventricular function in patients with hyperuricemia |
| Wu Ping |
| () |
| Abstract: |
| Objective To assess the value of three-dimensional speckle tracking echocardiography (3D-STE) in evaluating the left ventricular (LV) function in hyperuricemia patients. Methods We enrolled 40 healthy controls and 80 hyperuricemia patients and collected and analyzed full-volume 3D-STE images of the left ventricle in the apical four-chamber heart view. Laboratory tests and 3D-STE parameters, including stroke volume (SV), global longitudinal strain (GLS), and global circumferential strain (GCS), were compared between hyperuricemia patients and healthy controls. Results Hyperuricemia patients exhibited higher body mass index (24.70?±?2.9 vs. 21.83?±?2.4 kg/m2, P?=?0.001), C-reactive protein (5.82?±?9.4 vs. 1.12?±?1.8 g/L, P?=?0.012), alanine transaminase (34.26?±?26.6 vs. 17.60?±?13.0 U/L, P?=?0.011), aspartate transaminase (24.90?±?11.3 vs. 17.70?±?4.1 U/L, P?=?0.001), blood urea nitrogen (5.11?±?1.6 vs. 4.18?±?0.6 mmol/L, P?=?0.046), and serum creatinine (90.25?±?14.6 vs. 77.93?±?10.8 μmol/L, P?=?0.006) levels, as well as a lower estimated glomerular filtration rate (87.87?±?16.5 vs. 103.64?±?11.3 mL/min/1.73m2, P?=?0.002). The 3D-STE parameters reflecting LV function, including SV (54.71?±?9.6 vs. 61.92?±?14.4 mL, P=?0.024), GLS (??20.51?±?4.0 vs. ??23.20?±?4.0%, P?=?0.019), and GCS (??31.30?±?5.0 vs. ??35.65?±?2.5%, P
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