Objective：To explore the application value of contrast-enhanced ultrasound and shear-wave elastography (SWE) in the evaluation of chronic hepatitis B (CHB) liver fibrosis. Methods：A total of 120 patients with CHB admitted to our hospital from January 2015 to December 2018 were selected, and they were given contrast-enhanced ultrasound and SWE, and the hepatic arteriovenous transit time (HAVTT) and liver elasticity measurement value were obtained. Results： With the increase of liver fibrosis stage, HAVTT1 and HAVTT2 were gradually shortened, and liver elasticity measurement value was gradually increased. There were statistically significant differences in the HAVTT1, HAVTT2 and liver elasticity measurement value between any two groups among non-fibrosis group, fibrosis group and cirrhosis group (P<0.05). ROC curve analysis showed that the values of area under the curve of HAVTT1 and HAVTT2 in the diagnosis of liver fibrosis and cirrhosis were 0.870 and 0.851 and 0.889 and 0.856 respectively, and the values of area under the curve of liver elasticity measurement value in the diagnosis of liver fibrosis and cirrhosis were 0.953 and 0.898 respectively. The diagnostic efficacy of liver elasticity measurement value was significantly better than that of HAVTT1 and HAVTT2 (P<0.05). Conclusion：SWE is superior to contrast-enhanced ultrasound in the diagnosis of liver fibrosis and cirrhosis.