Objective：To investigate the value of two-dimensional speckle tracking imaging and myocardial contrast echocardiography in the evaluation of early left ventricular recovery after percutaneous coronary intervention （PCI） in patients with chronic total occlusion （CTO）. Methods：A total of 39 patients with CTO lesions who underwent PCI revascularization were enrolled. conventional two-dimensional echocardiography，two-dimensional speckle tracking imaging and myocardial contrast echocardiography were performed within 72 hours pre- and post-PCI revascularization on them，acquiring and saving images，measuring and calculating the left ventricular fuction parameters, Then compared all of the parameters between the pre-PCI and post-PCI. According to the CTO lesions in different coronary vessels were repatency，the patients were divided into three groups，regional myocardial longitudinal strain （RLS） and regional myocardial perfusion（PSI，A，β，A·β） at pre-PCI and post-PCI were calculated and compared respectively. Results At post-PCI，E-peak velocity and A-peak velocity of mitral valve，e ?S，e ?，e ?L，E/e ? ratio，LVEDV，LVESV，LVEF，WMSI were not statistically different from those before PCI. The post-PCI PSI was significantly lower， The GLS，A，β，A·β were significantly increased compared with pre-PCI， the difference was statistically significant. Among the three groups of patients in the LAD group，RCA group and LCX group，the RLS，PSI，A，β，A·β of each coronary artery donated area were significantly improved compared with the pre-PCI，P values were all less than 0.05，the difference were statistical significance. Conclusions PCI revascularization can improve myocardial perfusion and myocardial motor function in patients with CTO lesions. Both myocardial contrast echocardiography and two-dimensional speckle tracking imaging can evaluate the improvement early and quantitatively，and can simultaneously evaluate the left ventricular global and regional myocardium perfusion changes and strain changes.