摘要: |
目的:对比分析三维超声造影断层成像(Three-dimensional contrast-enhanced tomographic ultrasound imaging,3D-CETRUS TUI)与多参数磁共振(Multi-parameter magnetic resonance imaging,mp-MRI)对不同血清前列腺癌特异抗原(PSA)区间亚组患者的诊断价值。
方法:前瞻性顺序纳入2017年4月-2018年10月间于我院就诊的131例临床疑似前列腺癌患者,所有病例均常规行3D-CETRUS TUI及mp-MRI检查后接受经直肠超声引导下经会阴前列腺12针系统穿刺活检术,以穿刺病理结果为金标准,分析三个不同PSA区间亚组(420ng/ml)中两种方法诊断前列腺癌的结论差异。
结果:3D-CETRUS TUI与mp-MRI对前列腺癌诊断的整体灵敏度分别为78.05%、84.10%,整体特异度分别为77.55%、65.30%,阳性预测值分别为70.2%、78.6%,阴性预测值分别为83.9%、80.4%。准确度分别为:78.6%、83.2%。两者ROC曲线下而积比较,Z值等于0.290,P 值为 0.7718,差异无统计学意义。在范围420ng/ml中,两种方法均诊断正确。
结论:在部分PSA水平区间中,3D-CETRUS TUI能获得与mp-MRI相似的诊断结论,且更加快速、高效,有望成为前列腺癌诊断及评估的又一重要影像学诊断方法。 |
关键词: 三维超声造影 超声断层成像 多参数磁共振 |
DOI: |
投稿时间:2019-07-12修订日期:2019-07-26 |
基金项目:福建省自然科学基金 |
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Comparative study of dynamic intracavitary three-dimensional contrast-enhanced tomographic ultrasound imaging and multi-parameter magnetic resonance imaging in the diagnosis of prostate cancer |
CHEN MING,XU JINYANG,LV GUORONG,YANG SHUPIN,SHEN HAOLIN |
(Zhangzhou Affiliated Hospital of Fujian Medical University) |
Abstract: |
Objective:To compare the diagnostic value of three-dimensional contrast-enhanced tomographic ultrasound imaging(3D-CETRUS TUI) and multiparametric magnetic resonance imaging(mp-MRI) in patients with different serum prostate cancer specific antigen (PSA) level.
Methods: 131 patients with suspected prostate cancer in our hospital from April 2017 to October 2018 were included in this prospective study. All cases underwent 3D-CETRUS TUI and mp-MRI examination and transperineal prostate 12 needle system puncture under the guidance of transrectal ultrasound. According to the gold standard of puncture pathological results, three different PSA level groups (4 < PSA≤10 ng/ml、1020ng/ml) were analyzed.
Results: The overall sensitivity of 3D-CETRUS TUI and mp-MRI in the diagnosis of prostate cancer was 78.05%, 84.10%, and the overall specificity was 77.55% and 65.30%. The sensitivity of 3D-CETRUS TUI and mp-MR in the diagnosis of prostate cancer were 64.40%, 78.72% and 79.40%, 89.33% respectively in the range 4 20 ng/ml group, both methods were correctly diagnosed.
Conclusion:In some PSA levels, 3D-CETRUS TUI can obtain similar diagnostic conclusions as mp-MRI, and it is more rapid and efficient, so it is expected to become another important imaging diagnosis method for the diagnosis and evaluation of prostate cancer. |
Key words: three-dimensional contrast-enhanced ultrasound, tomographic ultrasound imaging,multi-parameter magnetic resonance imaging |