| 摘要: |
| 摘 要 目的 探讨超声三维斑点追踪技术评估不同室壁厚度主动脉瓣狭窄患者的左室收缩功能。方法 45例左室射血分数（LVEF）正常的重度主动脉瓣狭窄患者，按照室壁厚度分为狭窄组（A组，20例）及狭窄壁厚组（B组，25例），另选取年龄、性别相匹配的健康志愿者30例为对照组。所有研究对象均行常规及三维超声心动图检查，测量左室射血分数（LVEF）、左室心肌质量（LVM）、左室整体峰值纵向应变（GLS）、圆周应变（GCS）、面积应变（GAS）及径向应变（GRS）。并计算左室心肌质量指数（LVMI）。结果 与对照组相比，A、B组GLS、GRS显著降低（P<0.01），GCS、LVMI显著增加（P<0.01），LVEF、GAS各组比较无明显差异（P>0.05），B组与A组相比GLS显著降低（P<0.01），GRS、GAS、GCS无明显差异（P>0.05）。GLS、GRS、GCS及GAS与LVMI具有显著相关性，相关系数分别为（r=0.58、0.31、0.29、0.43，P<0.05）。结论 LVEF正常时，AS患者心脏收缩功能已经受损，并且室壁越厚，心肌质量越重，心功能受损越明显。 |
| 关键词: 三维斑点追踪技术 主动脉瓣狭窄 心室功能，左 |
| DOI： |
| 投稿时间：2019-07-29修订日期：2020-01-03 |
| 基金项目: |
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| Evaluation of left ventricular function in patients with aortic stenosis withdifferent wall thickness by three dimensional speckle tracking imaging |
| Jiang Yanna,Huang Puzhong,Zhao Yang |
| (Department of Ultrasound,Liaoning Jinqiu Hospital) |
| Abstract: |
| 【Abstract】Objective The aim of this study was to determine the capability of three dimensional speckle tracking imaging for evaluation of early myocardial dysfunction triggered by increased left ventricular wall thickness in severe aortic stenosis with normal LV ejection fraction. Methods Forty-five patients with severe aortic stenosis with normal left ventricular ejection fraction (LVEF) were divided into normal LV wall thickness group (A group ,20 cases) and increased LV wall thickness group (B group ,25 cases).Another 30 healthy volunteers matched in age and sex were selected as control group. ALL groups were performed two and three dimensional imaging, LVEF, LVM, GLS, GCS, GAS, GRS were obtained. Left ventricular mass index (LVMI) was calculated. Results GLS, GRS were
significantly reduced(P<0.01) and GCS,LVMI were significantly increased(P<0.01) in severe AS groups compared with controls. LVEF and GAS were similar in each groups (P>0.05). B group had lower GLS than A group (P<0.01),but GRS, GAS and GCS were no significant difference(P>0.05).GLS,GRS, GCS and GAS have significant correlation with LVMI(r=0.58,0.31,0.29,0.43,P<0.05). Conclusion When LVEF is normal, the left ventricular systolic function of severe AS patients has been impaired, and patients with increased LV wall thickness and the heavier LVMI were more obvious. |
| Key words: Three-dimensional speckle tracking imaging, Aortic stenosis, Ventricular function,left |
