| 摘要: |
| 探讨超声造影（CEUS）时间-强度曲线对早期宫颈癌（T1和T2期）诊断的价值。 方法 选取我院2016年1月至2018年12月收治的早期宫颈癌患者40例，宫颈良性肿瘤患者65例。所有患者均行经阴道超声和CEUS检查，定量分析CEUS时间强度曲线参数包括达到时间（TTP）、峰值强度（PI）、最大峰值强度比（PI/PIc）、曲线下面积（AUCTC）和平均渡越时间（MTT）。采用t检验或2或Fisher’s确切概率法比较两组间的差异。 结果 所有患者肿瘤平均直径为（2.93±1.22）cm。早期宫颈癌组较良性肿瘤组患者TTP明显缩短、PI明显增高、PI/PIc显著增大，差异具有统计学差异（P＜0.05），而两组患者AUCTC和MTT无显著统计学差异（P＞0.05）。 结论 CEUS时间-强度曲线参数TTP越短、PI越强、PI/PIc越高提示早期宫颈癌可能，三者可作为早期宫颈癌和良性肿瘤的鉴别诊断指标，并为宫颈癌的临床分期提供诊断依据。 |
| 关键词: 早期宫颈癌 良性肿瘤 超声造影 时间-强度曲线 |
| DOI： |
| 投稿时间：2019-08-02修订日期：2019-08-02 |
| 基金项目: |
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| Diagnostic performance of contrast enhanced ultrasound for detection of early cervical cancer |
| xieyingdong,xuchaoli,yangbin,zhanglijuan |
| () |
| Abstract: |
| To investigate the diagnostic performance of contrast enhanced ultrasound (CEUS) for detection of early cervical cancer (T1 and T2 stage). Methods 40 patients with early cervical cancer and 65 patients with benign tumor were enrolled between Jan 2016 and December 2018. CEUS and B mode transrectal ultrasound were performed. The time intensity curve parameters of CEUS with peak time of arrival (TTP), peak intensity of enhancement (PI), maximum peak intensity ratio (PI/PIc), area under the curve (AUCTC) and mean transit time (MTT) were recorded. t test or 2 or Fisher’s test were used to compare the differences between groups. Results The average diameter of all tumors was (2.93±1.22) cm. The shorter TTP, stronger PI, and higher PI/PIc were significantly observed in cervical cancer patients than benign tumor patients (P＜0.05). However, the AUCTC and MTT were no significant differences between n groups (P＞0.05). Conclusion The CEUS parameters with shorter TTP, stronger PI, and higher PI/PIc were associate with early cervical cancer, which can be used for differentiating cervical cancer from benign lesions, and provide the diagnosis basis for the clinical stage of cervical cancer. |
| Key words: early cervical cancer benign tumor contrast enhanced ultrasound time intensity curve |
