To investigate the diagnostic performance of contrast enhanced ultrasound (CEUS) for detection of early cervical cancer (T1 and T2 stage). Methods 40 patients with early cervical cancer and 65 patients with benign tumor were enrolled between Jan 2016 and December 2018. CEUS and B mode transrectal ultrasound were performed. The time intensity curve parameters of CEUS with peak time of arrival (TTP), peak intensity of enhancement (PI), maximum peak intensity ratio (PI/PIc), area under the curve (AUCTC) and mean transit time (MTT) were recorded. t test or 2 or Fisher’s test were used to compare the differences between groups. Results The average diameter of all tumors was (2.93±1.22) cm. The shorter TTP, stronger PI, and higher PI/PIc were significantly observed in cervical cancer patients than benign tumor patients (P＜0.05). However, the AUCTC and MTT were no significant differences between n groups (P＞0.05). Conclusion The CEUS parameters with shorter TTP, stronger PI, and higher PI/PIc were associate with early cervical cancer, which can be used for differentiating cervical cancer from benign lesions, and provide the diagnosis basis for the clinical stage of cervical cancer.