| 摘要: |
| 目的 探讨超声引导下假性动脉瘤内注药封堵术的安全性和有效性。方法 对2015年至2018年在陆军军医大学第二附属医院超声科行超声引导下凝血酶注射治疗的354例医源性假性动脉瘤患者的临床资料进行回顾性分析。结果 21.8%的患者诊断为复杂性假性动脉瘤（77/354），2例患者同时合并动静脉瘘。凝血酶注射剂量50~800UI，平均（213.6±124.2）UI，首次治疗成功率92.9%（329/354）。单纯性假性动脉瘤与复杂性假性动脉瘤治疗成功率之间差异无统计学意义（p＞0.05）。假性动脉瘤大小与凝血酶使用剂量之间存在一定相关性(p=0.01)。凝血酶注射后临床及超声检查未发现并发症发生的确切证据，假性动脉瘤闭塞后未发现肢体血液供应恶化。结论 超声引导下假性动脉瘤内注药封堵术是一种安全有效的治疗方法。 |
| 关键词: 假性动脉瘤 凝血酶 超声 |
| DOI： |
| 投稿时间：2019-08-04修订日期：2019-08-25 |
| 基金项目: |
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| Safety and efficacy evaluation of ultrasound-guided thrombin injection into pseudoaneurysm |
| CHEN xiaoqin,LIU zheng,ZHANG jie,PAN xv,GONG jinling |
| (Department of Ultrasound,the second affiliated Hospital of Army Medical University) |
| Abstract: |
| Objective To investigate the safety and efficacy of ultrasound-guided injection thrombin injection into pseudoaneurysm (PA). Methods The clinical data of 354 patients with iatrogenic pseudoaneurysm who were treated with ultrasound-guided thrombin injection in the Department of Ultrasound, the second affiliated Hospital of Army Medical University from 2015 to 2018 were analyzed retrospectively. Results 21.8% of the patients were diagnosed with complex pseudoaneurysm (77 / 254), and 2 patients were complicated with arteriovenous fistula. The injection dose of thrombin was 50 to 800 UI, with an average of (213.6 ±124.2) UI. 92.9% of patients were successfully treated during the initial thrombin injection. There was no significant difference in the success rate between simple pseudoaneurysm and complex pseudoaneurysm (p>0.05). There is a certain correlation between the size of pseudoaneurysm and the dose of thrombin (p=0.01). No definite evidence of complications was found in clinical and ultrasonic examination after thrombin injection, and no deterioration of blood supply in extremities was found after pseudoaneurysm occlusion. Conclusion Ultrasound-guided thrombin injection into pseudoaneurysm is a safe and highly effective method. |
| Key words: pseudoaneurysm thrombin ultrasound |
