| 摘要: |
| 目的 探讨前列腺增生患者前列腺移行区及周围区组织药物治疗前后弹性模量的变化。 方法 选取2017年7月至2019年1月在浙江省医疗健康集团长兴医院确诊为前列腺增生并口服药物治疗的患者175例。采用经直肠实时剪切波弹性超声成像技术测量移行区和周围区前列腺组织的弹性模量。比较患者治疗前后前列腺增生程度变化,分析药物治疗前后患者前列腺组织移行区和周围区弹性模量的影响,分析前列腺组织移行区、周围区弹性模量与患者IPSS、QOL评分、最大尿流率、前列腺体积、剩余尿量的相关性。结果 药物治疗后患者前列腺组织移行区和周围区弹性模量分别由(59.20±6.03)、(25.04±2.89)kPa,降至(39.66±6.03)、(14.46±3.01)kPa两组变化差异均有统计学意义(P<0．05)。前列腺组织移行区弹性模量与IPSS评分、QOL评分、Qmax、PV、PVR有显著相关性(r值分别为0.74、0.82、-0.75、0.51、0.77,P均<0．05),而前列腺周围区组织弹性模量与IPSS评分、QOL评分、Qmax、PV、PVR相关性较弱(r值分别为0.57、0.73、-0.62、0.42、0.53,P均<0．05)。 结论 实时剪切波弹性超声成像技术能够提供前列腺增生患者药物治疗前后的前列腺组织硬度信息、评估药物治疗前列腺增生的治疗效果。 |
| 关键词: 弹性成像 前列腺增生 IPSS QOL |
| DOI： |
| 投稿时间：2019-08-08修订日期：2019-08-08 |
| 基金项目: |
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| Use of real-time shear wave elastography on quantitative evaluation of treatment effect of medicine on benign prostatic hypertrophy patients |
| Zhang-Yamin,Tang-Yun,Li Bing |
| () |
| Abstract: |
| Objective To compare the changes of Young’S modulus of transitional and peripheral zone of prostate in benign prostatic hyperplasia patients after medicine treatment. Methods A 175 benign prostatic hyperplasia patients who underwent transrectal shear wave elastography were selected in Changxing Hospital of Zhejiang Medical and Health Group from July 2017 to January 2019．Young"s modulus of transitional zone and peripheral zone of prostate was measure by real-time shear wave elastography before and after medicine treatment. Young’S modulus of transitional zone and peripheral zone of prostate were compared and their correlation with IPSS、QOL、PV、PVR、Qmax were evaluated． Results The mean Young"s modulus of prostate transitional zone and peripheral zone were from (59.20±6.03)、(25.04±2.89) kPa to (39.66±6.03)、(14.46±3.01) kPa after medicine treatment. Young"s modulus of prostate transitional and peripheral zone decreased gradually with the decrease of IPSS, QOL, PV,PVR and increase of Qmax but Young’S modulus of transitional Zone changed more significantly．Young"s modulus of transitional zone showed a significant correlation with IPSS, QOL,Qmax, PV,PVR(r values were 0.74、0.82、-0.75、0.51、0.77,P<0．05),and Young"s modulus of prostate peripheral zone showed a weak correlation with#$NLIPSS, QOL,Qmax, PV,PVR(r values were 0.57、0.73、-0.62、0.42、0.53,P<0．05)． |
| Key words: shear wave elasticity imaging benign prostatic hyperplasia IPSS QOL |
