| 摘要: |
| 目的 研究经直肠实时组织弹性成像(TRTE)、定量参数峰值应变指数(PSI)在前列腺癌(PCa)诊断中的应用价值。方法 回顾性分析本院100例疑似PCa患者临床资料,所有患者均接受经直肠超声(TRUS)和TRTE超声检查,记录患者TRUS和TRTE影像特点。以穿刺活检结果为金标准,比较两种检查方法的准确性。计算PSI值,分析PSI判断前列腺病灶性质的准确性。结果 病理活检结果显示PCa 84例,前列腺良性病灶16例。TRUS和TRTE与病理结果均具有较好的一致性(Kappa = 0.612,0.797；P均 = 0.000)。TRUS和TRTE诊断PCa的灵敏度、特异度及准确度比较,差异均无统计学意义(P > 0.05)。PCa病变TRTE表现为病灶处呈局部蓝色或被蓝色覆盖,PSI判断前列腺病灶性质的AUC为0.854(95%CL = 0.735-0.973,S.E. = 0.061,P = 0.000),灵敏度为0.813,特异度为0.786,最佳截断值为11.75。PSI诊断PCa的灵敏度显著高于TRUS检查方法,差异有统计学意义(P ＜ 0.05)。结论 TRTE结合PSI定量参数诊断PCa准确性高,有助于提高阳性检出率。 |
| 关键词: 经直肠实时组织弹性成像 定量参数峰值应变指数 前列腺癌 |
| DOI： |
| 投稿时间：2019-08-08修订日期：2019-09-02 |
| 基金项目: |
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| The application value of TRTE combined with PSI in the diagnosis of prostate cancer |
| Wang-ying,Xu-bing,Kang Hui-li,Cai Qiu-qiong,Mei Jiang-jun,Zhao Yun-xin,Yao Guang-li,Jiang yi |
| (Ultrasound Department,Punan Hospital,Pudong New Area) |
| Abstract: |
| Objective To study the application value of transrectal real-time tissue elastography (TRTE) and quantitative parameter peak strain index (PSI) in the diagnosis of prostate cancer (PCa).Methods The clinical dataes of 100 suspected PCa patients in our hospital were retrospectively analyzed,all patients received the transrectal ultrasonography (TRUS) and TRTE ultrasonography.The TRUS and TRTE imaging characteristics of patients were recorded.The accuracy of the two methods was compared,which accorded to the gold standard of puncture biopsy results.The PSI value was calculated and the accuracy of PSI in judging the nature of prostate lesions was analyzed.Results There were 84 cases of PCa of pathological biopsy and 16 cases of benign prostate lesions.There were good agreement between TRUS,TRTE and the pathological results (Kappa = 0.612,0.797;P = 0.000).There were no significant difference in sensitivity, specificity and accuracy between TRUS and TRTE in the diagnosis of PCa (P > 0.05).The TRTE manifestations of PCa lesions were locally blue or covered with blue,the AUC of PSI to judge the nature of prostate lesions was 0.854 (95%CL = 0.735-0.973,S.E. = 0.061,P = 0.000),the sensitivity was 0.813, specificity was 0.786, and the best truncation value was 11.75.The sensitivity of PSI in the diagnosis of PCa was significantly higher than that of TRUS.,the difference was statistically significant (P < 0.05).Conclusion The TRTE combined with PSI quantitative parameters can improve the accuracy of PCa diagnosis and help to improve the positive detection rate. |
| Key words: transrectal real-time tissue elastography quantitative parameter peak strain index prostate cancer |
