| 摘要: |
| 目的 应用脉搏波传导速度评估重度子痫前期 (Severe pre-eclampsia, SPE) 患者颈动脉弹性。 方法 随机选取重度子痫前期患者64例作为病例组,选取31例正常妊娠孕妇作为对照组(Normal pregnancy, NP),所有研究对象均于产前、产后12周记录一般临床资料并行双侧颈总动脉超声检查,使用M型超声获取双侧颈总动脉中段收缩末期内径(End-systolic Diameter ,Ds)、舒张末期内径(End-diastolic Diameter ,Dd),使用QIMT技术获取双侧颈总动脉中段平均内中膜厚度(Intima-media thicknes s,IMT),计算脉搏波传导速度(One-point pulse wave velocity ,PWVβ)并进行统计学分析。结果 与NP组产前相比,SPE组产前体重、体质量指数(Body Mass Index, BMI)、PWVβ均增大,差异有统计学意义(均p<0.05)；与NP组产后相比,SPE组产后体重、BMI、PWVβ均增大,差异有统计学意义(均p<0.05)；与SPE组产前相比,SPE组产后体重、BMI、PWVβ均减小,差异有统计学意义(均p<0.05)；与NP组产前相比,NP组产后体重、BMI减低,差异有统计学意义(均p<0.05)。 结论 重度子痫前期患者产前颈动脉弹性已经受损,产后平均21.79周颈动脉弹性虽有明显恢复但未恢复至正常妊娠史妇女产后同期状态。 |
| 关键词: 颈动脉弹性 重度子痫前期 脉搏波传导速度 |
| DOI： |
| 投稿时间：2019-10-15修订日期：2019-11-08 |
| 基金项目:山西省科技攻关项目(社会发展)(20130313061-10) |
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| Evaluate carotid artery elasticity of women with severe preeclampsia by pulse wave velocity |
| Zhao Xiaoyu,Xu Jianping,Dou Shuixiu,Ding Lingru,Du Yaqian,Zhang yingan,He yinfang |
| (Department of Ultrasonography,the First Hospital of Shanxi Medical University) |
| Abstract: |
| Purpose The aim of the study was to investigate in the severe preeclampsia the carotid artery elasticity using pulse wave velocity. Methods The study involved Sixty-four patients with severe preeclampsia as case group, and Thirty-one age- and gestational weeks- matched normal controls. The subjects were completed the clinical datas and carotid ultrasound scans in prenatal and 12 weeks after delivery, Intima-media thickness(IMT)、End-systolic diameter(Ds)、End-diastolic diameter(Dd) were measured by Quality intima-media thickness(QIMT) and M-mode ultrasound, and then calculated One-point pulse wave velocity (PWVβ) and analyzed them. Results Compared with the control group in prenatal , the parameters of SPE group in prenatal such as Weight、BMI(Body Mass Index)、PWVβ were increased(p<0.05); Compared with the control group after delivery , the parameters of SPE group after delivery such as Weight、BMI、PWVβ were increased(p<0.05); Compared with SPE group before delivery, the parameters of SPE group after delivery such as Weight、BMI、 PWVβ were decreased (p<0.05); Compared with control group before delivery, the parameters of control group after delivery such as weight、BMI、HR were decreased(p<0.05). Conclusion Carotid arterial stiffening could be seen in severe preeclampsia,which could be recovered incompletely on average 21.79 weeks after delivery. |
| Key words: Arterial elasticity Preeclampsia Pulse wave velocity |
