| 摘要: |
| 目的：评估成人血友病患者关节的超声HEAD-US-C评分与其临床功能评分的相关性。方法：本研究采用超声HEAD-US-C评分对40例成人血友病患者的膝、肘、踝关节进行超声评分,并采用血友病关节健康评估表2.1版(HJHS 2.1)及功能独立性评分表(FISH)对关节功能状况进行评估。结果:评估了40例患者的240个关节,HEAD-US-C评分为22.50(8.00,30.50),HJHS评分为31.50(15.50,46.75),FISH评分为27.00(21.50,32.00)。轻度与中度、重度之间的HEAD-US-C评分、HJHS评分及FISH评分均有显著差异(P<0.001)。A、B型血友病患者之间的HEAD-US-C评分与HJHS评分、FISH评分差异无明显统计学意义(r=0.844,r=-0.825,P<0.001)。膝关节和肘关节、踝关节的HEAD-US-C评分与HJHS评分、FISH评分均显著相关 (P<0.001)。结论：超声HEAD-US-C评分与HJHS、FISH评分具有很好的相关性,可以更客观地为临床提供有价值的关节损伤情况评估。 |
| 关键词: 血友病 超声 FISH HJHS |
| DOI： |
| 投稿时间：2019-11-17修订日期：2019-12-09 |
| 基金项目: |
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| The correlation between ultrasound score and clinical function in adult hemophiliac arthropathy |
| Fang Yunmei,Guo Yulin,Zhang Cuiming |
| () |
| Abstract: |
| Purpose: The aim of this study was to evaluate the correlation between HEAD-US-Cscore and the clinical function score in adult hemophiliacs joints.Methods: in this study, the knee, elbow and ankle of 40 adult hemophilia patients were evaluated by Hemophilic Early Arthropathy Detection with UltraSound in China( HEAD-US-C ),the joint function was evaluated by Hemophilia Joint Health Scores 2.1(HJHS 2.1) and The Functional Independence Score for Haemophilia (FISH).Results: We evaluated 240 joints in 40 patients,HEAD-US-C score was 22.50(8.00,30.50), HJHS score was 31.50(15.50,46.75), and FISH score was 27.00(21.50,32.00). HEAD-US-C score, HJHS score and FISH score in mild patients were significantly different from moderate patients and severe patients (P<0.001). There was no statistically significant difference between HEAD-US-C score, HJHS score and FISH score between patients with hemophilia A and B (r=0.844, r=-0.825, P<0.001).The HEAD-US-C scores of knee, elbow and ankle were significantly correlated with HJHS score and FISH score (P<0.001).Conclusion: HEAD-US-C score has a good correlation with HJHS score and FISH score, and ultrasound can provide more objective evaluation of joint injury. |
| Key words: Hemophilia Ultrasound FISH HJHS |
