| 摘要: |
| 目的：利用二维斑点追踪成像技术（two-dimentional speckle-tracking imaging，2D-STI）评价糖尿病患者左房结构和功能的改变。
资料和方法：纳入我院住院治疗的单纯糖尿病患者25例（A组），糖尿病有心肌损害的患者即糖尿病性心肌病（diabetic cardiomyopathy，DCM）患者30例（B组）、以及健康志愿者20例（C组）。获取心尖四腔心二维切面，利用后处理软件，分别获得三组的左房峰值应变（Ss），左房收缩期峰值应变率（s-SR），左房舒张早期峰值应变率（e-SR），以及舒张晚期峰值应变率（a-SR）。使用Simpson法估测左房最大容积。统计学方法采用独立样本T检验及方差分析。
结果：与正常对照组比较，糖尿病组、DCM组SS，s-SR、e-SR值均减低，P<0.001，差异具有统计学意义，B组较A组减低更明显；A组a-SR较B、C组增高，差异有统计学意义，B组与C组相比较，a-SR无统计学意义。
结论：糖尿病患者左房储存及管道功能减低，发展至DCM时，泵功能出现失代偿，2D-STI可以敏感地发现糖尿病患者左房功能的改变。 |
| 关键词: 二维斑点追踪成像技术 左房功能 糖尿病 |
| DOI： |
| 投稿时间：2019-11-29修订日期：2020-01-28 |
| 基金项目:山西省卫健委科研课题(No.2017062)；山西医科大学博士启动资金（No.03201646） |
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| Tow-dimensional Speckle Tracking Echocardiography in Evalution on Left Atrial Function in Changes in Patients with Diabetes |
| guohuali,QiaoYingyan,wangqian,HouZhimin,Li Xiaomei |
| () |
| Abstract: |
| Objective To investigate the changes of left atrial (LA) structure and function using two-dimentional ultrasound speckle-tracking imaging (2D-STI) in patients with diabetes. Methods 25 patients who suffer from pure diabetes without any heart disease and 30 patients with diabetic cardiomyopathy(DCM), 20 cases of healthy persons were included. All subjects were examined with 2D-STI to obstain the apical four chmber left atrium strain and strain rate curve image. Systolic strain and stain rate(Ss, s-SR), early diastolic stain rate(e-SR) and late diastolic strain rate(a-SR) were measured. Left atrial maximum volume obtained using Simpson. Independent - Sam- ples t Test and Analysis of Variance were used to perform the date analysis. Result Compared with the control group Ss, s-SR and e-SR decreased in diabetes and DCM, and the rection of DCM were more obvious. There was no significant different in a-SR, but different result appear where comparing diabetes group. Conclusions LA reservoir and conduit function was impaired in patients with diabetes，booster pump function were decompensated in DCM. 2D-STI can effectively assess the LA function in patients with diabetes. |
| Key words: Tow-dimensional speckle tracking imaging, Left atrial function, Diabetes. |
