| 摘要: |
| 目的 应用三切面超声应变分析技术评价肺动脉高压患者右心室功能，并探讨肺动脉高压对右心室功能的影响。方法 肺动脉高压患者68例，正常对照组68例，选取右室前游离壁-后间隔切面、中游离壁-中间隔切面及后游离壁-前间隔切面三个切面应用斑点追踪技术对纵向收缩峰值应变进行超声测量，得到整体及17节段应变值，进行组间比较。对右心室整体应变值与肺动脉收缩压进行相关性分析。结果 三切面斑点追踪技术测得肺动脉高压患者右心室整体应变、前游离壁基底段应变、中游离壁基底段应变、后游离壁基底段应变、前游离壁中段应变、中游离壁中段应变及中间隔基底段应变、前间隔基底段应变、中间隔中段应变、前间隔中段应变较对照组减低（P<0.05）。右心室三切面整体应变与肺动脉收缩压相关性较强（r=0.784，P<0.01）。结论 三切面斑点追踪技术多角度分析肺动脉高压患者右心功能具有可行性，为右心室整体及局部收缩功能的评价提供新的方法。 |
| 关键词: 肺动脉高压 右心功能 斑点追踪技术 三切面 |
| DOI： |
| 投稿时间：2019-12-04修订日期：2020-05-08 |
| 基金项目: |
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| Assessment of Right Ventricular Function in Patients with Pulmonary Arterial Hypertension by Speckle Tracking Imaging Derived from Three-section Echocardiography |
| fanxuanwei,wanglianyi,cuijian |
| () |
| Abstract: |
| Objective To evaluate the effect of pulmonary hypertension on right ventricular function in patients with pulmonary hypertension by using three-section echocardiography speckle imaging technology. Methods 68 pulmonary hypertension (PH) patients and 68 healthy controls receiving physical examination with matched basic information were enrolled as subjects for the ultrasonic evaluation of right cardiac function. Speckle tracking imaging technique was applied to measure the right ventricular longitudinal peak systolic strain of three sections: anterior free wall- posterior ventricular septum, middle free wall- middle ventricular septum, posterior free wall- anterior ventricular septum. The overall and 17-segment strain values were obtained and then compared between groups. The correlation between the global strain (GS) of right ventricular and the pulmonary arterial systolic pressure (PASP) was analyzed. Result Three-section speckle-tracking imaging technique proved through multi-angular measurement that the differences of global strain (GS) of right ventricle, basal segment strain of anterior free wall, basal segment strain of free wall, basal segment strain of posterior free wall, middle segment strain of anterior free wall, middle segment strain of free wall, basal segment strain of ventricular septum, basal segment strain of anterior ventricular septum, middle segment strain of ventricular septum, and middle segment strain of anterior ventricular septum between the two groups were statistically significant (P<0.05). Therefore, it was considered that the right ventricular GS and the above-mentioned segment strains in patients of the PH group were reduced from those in patients of the control group. The right ventricular GS presented strong correlation with PASP (P<0.01, r=0.784). Conclusion It is feasible to perform multi-angular analysis on the right cardiac functions of PH patients with three-section speckle-tracking imaging technique. This technology is also an innovative approach of evaluating the overall and regional systolic functions of right ventricle. |
| Key words: Pulmonary arterial hypertension Right ventricle Speckle tracking imaging three sections |
