| 摘要: |
| 目的 探讨中老年女性血尿酸水平与腹内脂肪含量及其他临床指标的相关性。方法 选取中老年女性256例，均行体格、血液及超声检查，获取其年龄、身高、体质量、腰围、臀围、血生化指标及左肾周脂肪囊面积等参数，根据有无SUA水平异常（女性＞360μmol/L），分为HUA组和非HUA组，比较两组上述参数的差异。采用二元Logistic回归分析影响高尿酸血症（HUA）患病率的独立危险因素。结果 HUA组24例，非HUA组323例，两组TG、左肾周脂肪囊面积和收缩压比较，差异均有统计学意义（均P<0.05）；其余参数比较差异均无统计学意义。二元Logistic回归分析显示HUA的发生与臀围、甘油三酯、血肌酐水平及左肾周脂肪囊面积独立相关（OR=1.078、2.079、1.104、1.384，均P<0.05）。结论 臀围和左肾周脂肪囊面积增加、甘油三酯和血肌酐水平升高可能是中老年女性HUA发生的独立危险因素。 |
| 关键词: 超声检查 高尿酸血症 腹内脂肪 中老年女性 |
| DOI： |
| 投稿时间：2019-12-09修订日期：2020-03-17 |
| 基金项目:北京市医院管理局“登峰”计划专项经费资助(DFL20151302) |
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| Study on the correlation between intra-abdominal Fat and Serum uric Acid in Middle-aged and elderly Women |
| Zhang Qian,Wang Xuemei,Wu Qingqing,Xu Shiyi,Liu Yanjun,Sun Lijuan,Wang Jingjing,WangLi |
| (Department of ultrasound,Beijing Obstetrics and Gynecology Hospital,Capital Medical University;Department of Ultrasound,the First Affiliated Hospital of China Medical University) |
| Abstract: |
| Objective To explore the correlation between the level of serum uric acid and the content of intra-abdominal fat and other clinical indexes in the middle-aged and elderly women. Methods A total of 256 middle-aged and elderly women were selected for physical, blood, and ultrasound examinations to obtain parameters such as age, height, body weight, waist circumference, hip circumference, blood biochemical indicators and left perirenal fat sac area.According to the presence or absence of abnormal SUA levels (Female＞360 μmol / L), they were divided into HUA group and non-HUA group, and the differences in the above parameters were compared between the two groups. Binary Logistic regression was used to analyze independent risk factors affecting the prevalence of hyperuricemia (HUA). Results There were 24 cases in the HUA group and 323 cases in the non-HUA group. There was a statistically significant difference in TG, left renal renal fat capsule area and systolic blood pressure between the two groups (all P<0.05); the other parameters were not statistically different. Binary logistic regression analysis showed that the occurrence of HUA was independently related to hip circumference, triglyceride, serum creatinine level, and area of left perirenal fat sac (OR = 1.078, 2.079, 1.104, 1.384, all P<0.05). Conclusion The increase of hip circumference，left perirenal fat sac area，triglyceride and serum creatinine levels may be independent risk factors for HUA in middle-aged and elderly women. |
| Key words: Ultrasonography hyperuricemia intra-abdominal fat middle-aged and elderly women |
