Congenital heart disease is the most common birth defect and the leading cause of early infant death. Fetal echocardiography has demonstrated a high prenatal detection rate for congenital heart disease. Clinical application of fetal echocardiography in prenatal diagnosis has greatly decreased the prevalence of severe complex congenital heart disease, contributed to making precise clinical therapy strategies for newborn with critical congenital heart disease so as to improve their preoperative hemodynamic status, and also provided the possibility of fetal cardiac intervention for congenital heart disease.