| 摘要: |
| 目的 探讨超声特征在涎腺肿瘤良恶性鉴别诊断中的价值。方法 回顾性分析经超声检查并手术病理证实的111例涎腺良性肿瘤和13例恶性肿瘤患者病历资料,比较良恶性病灶患者性别、年龄、最大径、纵横比、病灶数、回声均匀性、形态、边界、后方回声、囊性变、钙化灶和血流分级等指标,绘制受试者工作特征(ROC)曲线计算各指标的诊断效能。结果 两组在边界和钙化灶指标上差异有统计学意义(P＜0.05),边界指标诊断恶性肿瘤敏感度46.15%,特异度95.50%,准确率90.32%,曲线下面积为0.708。钙化灶指标诊断恶性肿瘤敏感度30.77%,特异度72.97%,准确率68.55%,曲线下面积为0.64。性别、年龄、最大径、纵横比、病灶数、回声均匀性、形态、后方回声、囊性变和血流分级等指标组间差异均无统计学意义(P＞0.05)。结论 超声诊断涎腺肿瘤良恶性较为困难,当肿瘤出现边界不清和内部多发钙化灶时需考虑为恶性。 |
| 关键词: 涎腺肿瘤 良恶性 超声 |
| DOI： |
| 投稿时间：2019-12-31修订日期：2019-12-31 |
| 基金项目:国家自然科学基金资助项目(编号81571677)；上海市松江区科技攻关项目(编号 18sjkjgg42)；上海市闵行区自然科学研究课题(编号2019MHZ085)；上海市闵行区中心医院院级课题(编号2018MHLC07) |
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| Application of ultrasonographic features in the differential diagnosis of benign and malignant salivary gland tumors |
| HAN MING LI,WANG DONG HUA,SHI QIU SHENG,CHEN HONG YAN,DU LIAN FANG |
| (Minhang Hospital, Fudan University) |
| Abstract: |
| Objective To evaluate the value of ultrasonography in the differential diagnosis of benign and malignant salivary gland neoplasms. Methods 124 patients with salivary gland tumors included 111 benign tumors and 13 malignant neoplasms were proved by surgical histopathology after the ultrasonography process. And the parameters including gender, age, maximum diameter, height/width ratio, number of lesions, echogenicity, shape, margin, posterior echogenicity, cystic degeneration, calcification and blood flow were retrospectively analysed. The receiver operating characteristic (ROC) curve was plotted to calculate the diagnostic efficacy of the parameters. Results There were statistically significant differences in the parameters of margin and calcification between the two groups (P＜0.05). The sensitivity, specificity, and accuracy of unclear margin in differentiation of malignant from benign neoplasms in the salivary gland were 46.15%, 95.50%, and 90.32%, respectively. The area under the curve was 0.708. Differentiating diagnoses between malignant and benign neoplasms with calcification resulted in a sensitivity of 30.77%, specificity of 72.97%, accuracy of 68.55%, and the area under the curve of 0.64. There were no statistically significant differences in gender, age, maximum diameter, height/width ratio, number of lesions, echogenicity, shape, posterior echogenicity, cystic degeneration and blood flow the groups (P＞0.05). Conclusion: It is difficult to diagnose salivary gland tumors by ultrasonography. Malignant neoplasms should be considered when the neoplasms have unclear boundaries and multiple calcifications. |
| Key words: Salivary gland neoplasms Benign and malignant Ultrasound |
