摘要: |
【摘要】目的:探讨超声引导下浅表淋巴结穿刺活检在儿童中的临床应用价值。方法:将195例患儿采用超声引导下浅表淋巴结穿刺活检,并结合其临床特点、术后病理学等资料进行综合分析。结果:1、195例患儿中,穿刺活检做出良性诊断病例166例,其中1例淋巴结结核为误诊;恶性病例21例;未做出诊断8例,漏诊1例霍奇金淋巴瘤。2、超声引导下穿刺在恶性肿瘤诊断中:灵敏度为95.5%,特异性为100%。阳性预测值为100%,阴性预测值为99.4%。3、195例中186例为正确诊断,诊断正确率为95.4%。取材满意时病理诊断准确率:99.4%(161/162),取材不满意时诊断准确率:75.8%(25/33),两者差异有显著统计学意义(χ2=29.5988,P<0.05)。加做免疫组化病理诊断正确率99.0%(99/100),未加做免疫组化病理诊断正确率为91.6%(87/95),两者差异有统计学意义(χ2=4.5253,P<0.05)。4、195例患儿无一例出现大出血或其他严重的并发症。5.颈部淋巴结病变中恶性、良性病例均累及Ⅱ区最多,分别占72.7% (8/11)、81.6%(71/87)。结论:超声引导下浅表淋巴结穿刺活检具有足够高的特异性及灵敏度,同时还有着操作简单、费用低廉、穿刺安全、儿童耐受良好等特点,具有广阔的应用前景。 |
关键词: 超声引导下穿刺活检 浅表淋巴结肿大 体格检查特征 儿童 |
DOI: |
投稿时间:2020-01-02修订日期:2020-12-05 |
基金项目: |
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Application value of superficial lymph node biopsy guided by ultrasound in children |
YAN Xue-Bo,SUN Yan,ZHANG Song,ZHAO Yan-Xia,ZHONG Ren,China.SUN Li-Rong |
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Abstract: |
【Abstract】Objective: To investigate the clinical value of ultrasound-guided superficial lymph node biopsy in children. Methods: The clinical features,postoperative pathology and other data of 195 patients underwent ultrasound-guided superficial lymph node biopsy were analyzed retrospectively. Results: 1. Among 195 children, 166 cases of benign diagnosis were made by needle biopsy, of which 1 case was misdiagnosed; 21 cases were malignant; 8 cases were not diagnosed, and 1 case was Hodgkin''s lymphoma.2. Ultrasound-guided biopsy in children with superficial lymph node malignancy: sensitivity is 95.5%, specificity is 100%. The positive predictive value was 100% and the negative predictive value was 99.4%. 3. 186 of 195 patients were diagnosed correctly, and the correct diagnosis rate was 95.4%. The accuracy rate of pathological diagnosis when the material is satisfactory: 99.4% (161/162), and the accuracy rate of diagnosis when the material is not satisfactory: 75.8% (25/33).The correct rate of immunohistochemical pathology was 99.0% (99/100), and the correct rate of immunohistochemical pathology was 91.6% (87/95). The difference was statistically significant (χ2=4.5253, P< 0.05).4. None of the 195 children developed major bleeding or other serious complications. 5. Malignant and benign cases of cervical lymph node lesions involved the most area Ⅱ, accounting for 72.7% (8/11) and 81.6% (71/87), respectively. Conclusion: Ultrasound-guided superficial lymph node biopsy had high specificity and sensitivity, which with the characteristics of easy and safe in operation, low in cost and good tolerance in children. Ultrasound-guided superficial lymph node biopsy had broad application prospects. |
Key words: Ultrasound-guided Puncture Pathology superficial lymphadenopathy Physical examination characteristics Children |