Objective To summarize the contrast-enhanced ultrasonic characteristics of of pleomorphic adenomas and warthin tumors of salivary gland. Methods 17 pleomorphic adenomas and 16 warthin tumors underwent contrast-enhanced ultrasound examination and confirmed by surgical histopathology， were retrospectively analyzed. Result The contrast-enhanced ultrasonographic of pleomorphic adenomas were mainly synchronal (76.47%), centripetal (64.71%), inhomogeneity (76.47%) and hypo-enhancement (70.59%), with clear boundary after enhancement (88.24%), visible enhancement rim (94.12%), and no increase in the mass scope after enhancement (88.24%). Warthin tumors was characterized by fast fill-in (50%), non-centrality (87.5%), inhomogeneity (62.5%), and hyper-enhancement (56.25%). After enhancement, the boundary was clear, the enhancement rim was visible, and the mass scope was not increased (93.75%). There were statistically significant differences in the enhancement direction and enhancement intensity between pleomorphic adenomas and warthin tumors（P＜0.05）. Conclusion The contrast-enhanced ultrasound of pleomorphic adenomas and warthin tumors have certain characteristics， and the enhancement direction and enhancement intensity parameters are helpful to differentially diagnose pleomorphic adenomas and warthin tumors．