| 摘要: |
| 探讨难治性甲亢患者超声影像学特征及其与相关血清学指标的相关性。方法 选取我院2016年1月~2018年1月收治的156例难治性甲亢患者为观察组，再选取同期于我院体检健康者121例为对照组，所有研究对象均经实验室检查和彩色多普勒超声检查。对比分析超声影像学特征、血清学指标总三碘甲腺原氨酸（TT3）、总甲状腺素（TT4）、游离三碘腺原氨酸（FT3）、游离甲状腺素（FT4）、促甲状腺素（TSH）水平，通过Pearson分析影像学特征与血清学指标的相关性。结果 观察组患者甲状腺体积、最高流速、管径显著高于对照组（P＜0.05），血流阻力指数略大于对照组，但比较无明显差异（P＞0.05）；观察组患者血清FT3、FT4、 TT3、TT4水平均显著高于对照组（P＜0.05），TSH水平显著低于对照组（P＜0.05）；经Pearson相关性分析，TSH与甲状腺体积、最高血流速度、管径大小呈负相关（r＜0，P＜0.05）；FT3、FT4、TT3、TT4与甲状腺体积、最高血流速度、管径大小均呈正相关（r＞0，P＜0.05）。结论 采用超声检查难治性甲亢患者甲状腺体积、最高血流速度、管径大小可较好反映难治性甲亢病情，为诊治和监测难治性甲亢提供可靠参考。 |
| 关键词: 难治性甲亢 超声影像特征 血清学指标 相关性 |
| DOI： |
| 投稿时间：2020-02-18修订日期：2020-03-06 |
| 基金项目: |
|
| Ultrasound Imaging Characteristics of Patients with Refractory Hyperthyroidism and Its Correlation with Related Serological Indicators |
| Yang xing yi |
| () |
| Abstract: |
| To investigate the ultrasound imaging characteristics of patients with refractory hyperthyroidism, and to analyze its correlation with related serological indicators. Methods 156 patients with refractory hyperthyroidism (observation group) and 121 healthy individuals (control group) in our hospital from January 2016 to January 2018 were enrolled. All the selected subjects received laboratory examination and color Doppler ultrasound. Various indexes were compared between groups, including ultrasound imaging characteristics, serological indicators total triiodothyronine (TT3), total thyroxine (TT4), free triiodothyronine (FT3), free thyroxine (FT4), and thyroid stimulating hormone (TSH). The correlation between imaging characteristics and serological parameters was analyzed by Pearson correlation analysis. Results The thyroid volume, maximum flow rate, and tube diameter of the observation group were significantly higher than those of the control group (P<0.05), and the blood flow resistance index of the observation group was slightly larger than that of the control group, with no significant difference (P>0.05); The levels of serum FT3, FT4, TT3, and TT4 in the observation group were significantly higher than those in the control group (P<0.05), and TSH levels were significantly lower than those in the control group (P<0.05); Pearson correlation analysis showed that TSH was negatively correlated with thyroid volume, maximum blood flow velocity, and tube diameter (r<0, P<0.05); FT3, FT4, TT3, and TT4 were positively correlated with thyroid volume, maximum blood flow velocity, and tube diameter (r>0, P<0.05); Conclusion Ultrasound examination of thyroid volume, maximum blood flow velocity and tube diameter of patients with refractory hyperthyroidism can reflect the severity of refractory hyperthyroidism, thus providing reliable reference for diagnosis, treatment and monitoring of refractory hyperthyroidism. |
| Key words: Refractory hyperthyroidism Ultrasound imaging characteristics Serological indicators Correlation |
