| 摘要: |
| 目的 应用超声三维斑点追踪成像技术（3D-STI）定量评价2型糖尿病（T2DM）患者左心室整体收缩功能的早期改变。方法 选取50例左心室收缩功能正常（LVEF≥50％）的T2DM患者（DMA组），30例左心室收缩功能减低（LVEF＜50％）的T2DM患者（DMB组）以及42例健康志愿者（NC组）。应用三维斑点追踪成像技术测量左心室的整体收缩期峰值纵向应变率（GLS）、径向应变率(GRS)、圆周应变率(GCS)以及面积应变率（GAS） 结果 与NC组比较，DMA GLS、GCS、GAS显著减低,而GRS显著增高(P ＜0.05)；DMB组GLS、GCS、GAS均显著减低(P＜0.05）,而GRS无差异(P ＞0.05）。且DMB组GLS、GCS、GRS、GAS均较DMA组显著减低（P＜0.05）。 结论 3D-STI可用于检测T2DM患者早期左室收缩功能的异常，是评估糖尿病患者早期心肌病变可靠方法。 |
| 关键词: 三维斑点追踪 2型糖尿病 左心室收缩功能 应变率 |
| DOI： |
| 投稿时间：2020-03-03修订日期：2020-03-18 |
| 基金项目: |
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| evaluation of left ventricular systolic function in patients with type-2 diabetes mellitus by three-dimensional speckle tracking imaging |
| chengzhenzhen,liuyong |
| () |
| Abstract: |
| Objective To quantitatively evaluate the early changes of of the left ventricle(LV) in patient with type-2 diabetes mellitus（T2DM）by three-dimensional speckle-tracking imaging(3DSTI) Methods 50 T2DM patients (DMA group) with normal left ventricular systolic function (LVEF≥50％%), 30 T2DM patients (DMB group) with reduced left ventricular systolic function (LVEF < 50%) and 42 healthy volunteers (NC group) were selected. The peak longitudinal strain rate (GLS), radial strain rate (GRS), circumferential strain rate (GCS) and area strain rate (GAS) of left ventricle were measured by three-dimensional speckle tracking technique.. Results C Compared with NC group, DMA GLS, GCS and GAS decreased significantly, while GRS increased significantly (P < 0.05). GLS, GCS and GAS in DMB group were significantly decreased (P < 0.05), while GRS had no difference (P > 0.05). In addition, GLS, GCS, GRS and GAS in DMB group were significantly lower than those in DMA group (P < 0.05) Conclusio 3D-STI can be used to detect early left ventricular systolic dysfunction in T2DM patients, and is a reliable method to evaluate early myocardial lesions in diabetic patients. |
| Key words: Speckle tracking imaging Diabetes mellitus Type 2 Left ventricular systolic function Stain rate |
