| 摘要: |
| 报告基因是超声成像基础研究中的一种重要工具，具有便捷、可靠、灵敏度高等优点，可对多种不同的生物学和分子遗传学过程进行显像。本文对多种报告基因在超声成像中的基础应用进展进行了综述，为该技术的进一步拓展生物医学应用提供新方法和思路。 |
| 关键词: 报告基因 超声成像 基因编码产物 伪空胞 |
| DOI： |
| 投稿时间：2020-03-08修订日期：2020-03-18 |
| 基金项目:国家重点研发计划课题(2017YFA0205201), 国家自然科学基金(NSFC)( 81925019, 81422023, 51273165, U1705281), 教育部新世纪优秀人才支持计划(ncet-13-0502). |
|
| Advances in the application of reporter genes for ultrasound imaging |
| Dengfeng Li,Xuan Liu,Gang Liu |
| (Center for Molecular Image and Translational Medicine,Xiamen University) |
| Abstract: |
| Reporter genes are crucial tools for ultrasound imaging research with the advantages of convenience, reliability and high sensitivity, which can image various biological and genetical processes at the molecular, cellular and multicellular levels. This review summarizes the developed reporter genes and the application for ultrasound imaging research, providing new clues and ideas for the further application in biomedical engineering. |
| Key words: Reporter genes Ultrasound Imaging Genes encoding products Gas vesicles |
