Objective To explore the value of gastroenterographic contrast echocardiography and calculate gastric emptying rate for assessing functional dyspepsia (FD). Methods Totally 128 patients with FD who were admitted to our hospital were involved as FD group and further divided into epigastric pain syndrome (EPS) subgroup (n=68) and postprandial discomfort syndrome (PDS) subgroup (n=60). In the same period, 65 healthy adults were involved as the control group. The total gastric cavity volume (TGCV) and gastric emptying rate of all subjects were measured when fasting, 0 min (immediately after the end of the trial meal), 30 min, 60 min, 90 min, 120 min after trial meal. After the end of the treatment, the gastric emptying rate of the FD patient was checked again and calculated. The ultrasound findings of gastric emptying in patients with different clinical types and different severity of FD were analyzed. Results The postprandial TGCV of both FD group and control group showed a decreasing trend, but the change of TGCV in the control group was significantly larger than that of FD group (P<0.05). The gastric emptying rate in the FD group was lower than that in the control group at 30 min, 60 min, 90 min, and 120 min. The gastric emptying rate in both groups increased with time, but the gastric emptying rates in the FD group at each time point were lower than those in the control group (all P<0.05). The 120-minute gastric emptying rate of patients in the EPS subgroup before treatment was significantly greater than that in the PDS subgroup. The mild patients were significantly larger than those in the severe patients. After treatment, the PDS subgroup was significantly larger than the EPS subgroup. All the differences were statistically significant (all P<0.05). There was no significant difference between patients with mild and severe patients (P>0.05). Conclusion Ultrasound gastrointestinal angiography and calculation of TGCV and gastric emptying rate are effective methods for the diagnosis of FD.