| 摘要: |
| 目的 应用三维斑点追踪技术(3D-STI)评价不同程度主动脉瓣狭窄患者的左室收缩功能。方法 纳入66例左室射血分数(LVEF)正常的主动脉瓣狭窄患者,按照狭窄程度分为轻度狭窄组(25例)、中度狭窄组(21例)及重度狭窄组(20例),另选取年龄、性别相匹配的健康志愿者30例为对照组。所有研究对象均行常规及三维超声心动图检查,测量左室射血分数(LVEF)、左室整体峰值纵向应变(GLS)、圆周应变(GCS)、面积应变(GAS)及径向应变(GRS)。 结果 与对照组相比,轻度狭窄组GLS降低,GRS、GCS及GAS无明显差异(P>0.05),与对照组及轻度狭窄组相比,中度狭窄组GLS、GRS降低(P<0.05),GCS增加(P<0.05),GAS无明显差异(P>0.05),与对照组、轻度狭窄组及中度狭窄组相比,重度狭窄组GLS、GRS降低(P<0.05),GCS增加(P<0.05),GAS无明显差异(P>0.05)。三维测得LVEF与GLS、GCS、GAS及GRS均具有显著相关性,相关系数分别为0.71、0.59、0.79、0.57(P<0.01)。 结论 主动脉瓣轻度狭窄时心脏功能既已受损,并且随狭窄程度的增加心脏功能受损越明显,3D-STI技术可对其进行早期评价。 |
| 关键词: 三维斑点追踪超声心动图 主动脉瓣狭窄 心室功能，左 |
| DOI： |
| 投稿时间：2020-03-28修订日期：2020-04-13 |
| 基金项目: |
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| Three-dimensional speckle tracking imaging in evaluation Left Ventricular Systolic Function in patients with different degrees of aorticstenosis |
| Jiang Yanna,Zhao Yang.,Xu Sheng |
| (Department of Ultrasound,Liaoning JinqiuHospital) |
| Abstract: |
| Objective To evaluate left ventricular systolic function in patients with different degrees of aortic stenosis(AS) by three-dimensional speckle tracking imaging(3D-STI). Methods Sixty-six AS patients with normal left ventricular ejection fraction (LVEF) were divided into mild (25 cases), moderate (21 cases) and severe(20 cases)AS groups.Another 30 normal subjects from regular physical examination were selected as control group. All groups were performed two and three dimensional imaging. Left ventricular ejection fraction (LVEF), global longitudinal strain(GLS), circumferential strain(GCS),area strain(GAS) and radial strain(GRS) were measured with 3D-STI .Results Compared with the control group,GLS in mild AS group decreased(P<0.05), GRS, GCS had no significant difference (P>0.05).Compared with control group and mild AS group, GLS and GRS in moderate AS group decreased (P<0.05), GCS increased (P<0.05). Compared with control group, mild and moderate AS groups, GLS and GRS decreased (P<0.05), GCS increased (P<0.05) in severe AS group. GAS had no significant difference in all groups(P>0.05).GLS, GCS, GAS and GRS were positively correlated with LVEF(r=0.71、0.59、0.79、0.57, P<0.01, respectively).Conclusion The left ventricular myocardial function have already impaired when AS is mild, and the damage is more obvious with the increase of stenosis degree.3D-STI can be used for early evaluation. |
| Key words: Three-dimensional speckle tracking imaging, Aortic stenosis,Ventricular function, left |
