| 摘要: |
| 目的：探讨肺超声评分预测新生儿发生呼吸窘迫综合征（NRDS）合并支气管肺发育不良（BPD）的临床价值。
方法：对158例NRDS患儿进行肺部超声检查，根据标准计算肺超声评分，并收集患儿一般临床资料。依据是否合并支气管肺发育不良（BPD）将其分为BPD组和非BPD组，对比两组患儿肺超声评分及临床资料的差异。分析肺超声评分预测NRDS合并BPD临床价值，并探讨肺超声评分与不同治疗方式之间的相关性。
结果：BPD组肺超声评分高于非BPD组 （P＜0.001）。两组患儿在胎龄、出生体重中均有差异（P＜0.05）。住院时长、持续气道正压呼吸及机械通气时间、Apgar评分这些因素中两组也均有差异（P＜0.05）。两组间性别、双胎数、常规氧疗时间，以及宫内感染、新生儿肺炎发生率差异无统计学意义 （P＞0.05）。肺超声评分预测BPD的ROC曲线下面积为0.832，最佳评分临界值37分,敏感度78%，特异度89%，阳性预测值86.7%，阴性预测值74.5%。患儿肺超声评分与采用的呼吸治疗方式之间呈正相关（r=0.47，P＜0.05）。
结论：肺超声评分法有助于预测NRDS患儿是否合并BPD，为重症患儿的呼吸治疗方式提供一定依据。 |
| 关键词: 新生儿，肺超声，呼吸窘迫综合征，支气管肺发育不良 |
| DOI： |
| 投稿时间：2020-04-14修订日期：2020-11-20 |
| 基金项目: |
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| Clinical value of pulmonary ultrasound score in predicting neonatal respiratory distress syndrome with bronchopulmonary dysplasia |
| WEI Jingli,LI Min,LIU Bailing,LI Na,HE Huan |
| (Department of Medical Ultrasound,Xi’an Children’s Hospital,Xi’an Shaanxi 710002;China) |
| Abstract: |
| Abstract: Objective To investigate the clinical value of pulmonary ultrasound score in predicting neonatal respiratory distress syndrome (NRDS) combined with bronchopulmonary dysplasia (BPD).Methods Lung ultrasonography was performed on 158 children with NRDS, and lung ultrasound scores were calculated according to standards, and general clinical data of the children were collected.Cases were divided into BPD and non-BPD groups based on whether they had bronchopulmonary dysplasia (BPD), the differences in pulmonary ultrasound scores and clinical data between the two groups were compared.The pulmonary ultrasound score was analyzed to predict the clinical value of NRDS combined with BPD, and the correlation between the pulmonary ultrasound score and different treatment methods was explored.Results Lung ultrasound scores in the BPD group were higher than those in the non-BPD group (P <0.001).There were significant differences in gestational age and birth weight between the two groups of children (P <0.05).There were also differences in the length of hospital stay, continuous positive airway pressure, mechanical ventilation time, and Apgar score (P<0.05).There were no significant differences in gender, number of twins, number of children receiving conventional oxygen therapy, and incidence of intrauterine infection and neonatal pneumonia between the two groups (P> 0.05).Pulmonary ultrasound score predicts the area under the ROC curve of BPD is 0.832, the best score cutoff is 37 points, sensitivity is 78%, specificity is 89%, positive predictive value, negative predictive value.There was a positive correlation between pulmonary ultrasound scores and respiratory therapy (r = 0.47, P <0.05).Conclusion Pulmonary ultrasound scoring method is helpful for predicting whether children with NRDS are associated with BPD and provides a basis for respiratory treatment in severe children. |
| Key words: neonate, pulmonary ultrasound, respiratory distress syndrome, bronchopulmonary dysplasia |
