| 摘要: |
| 目的 本文旨在探讨超声实时剪切波弹性成像（shear wave elastography,SWE）在胆道闭锁患儿术后早期胆管炎发生中的临床价值。
方法 我院2019年2月至2020年2月经超声诊断为胆道闭锁并手术病理证实的患儿共59例，应用实时弹性成像（SWE）测量术前及术后1月的肝杨氏模量值，并将患儿术后1月内是否出现胆管炎，分为胆管炎组及非胆管炎组，分别探究两组内及组间术前及术后1月的肝杨氏模量的变化情况。
结果 非胆管炎组与胆管炎组分别进行组内比较，术前与术后的肝杨氏模量值的差异均有统计学意义（P<0.05），且在胆管炎组与非胆管炎组术前的肝杨氏模量值没有显著差异的情况下，术后1月胆管炎组的肝杨氏模量值明显高于非胆管炎组（P=0.001），所有患儿术前肝杨氏模量值随日龄呈线性关系（R=0.258，P=0.000），日龄越大杨氏模量值越大，但日龄与术后1月肝杨氏模量值之间没有明显线性相关性（P=0.055）。
结论 超声实时剪切波弹性成像（shear wave elastography，SWE）技术在检测胆道闭锁患儿术后早期胆管炎发生的筛检中具有一定的价值。 |
| 关键词: 胆道闭锁 婴儿 弹性成像 |
| DOI： |
| 投稿时间：2020-04-15修订日期：2020-05-08 |
| 基金项目: |
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| Evaluate the value of real-time shear wave elastography in early postoperative cholangitis in children with biliary atresia |
| he huan,Liu Bailing,ZHANG ZHAN,LI MIN,WEI JINGLI |
| () |
| Abstract: |
| Objective To investigate the elastic changes in the liver of early cholangitis after biliary atresia (BA) operation. Methods 59 children who were diagnosed with biliary atresia in ultrasound and confirmed by operation from February 2019 to February 2020 were analyzed. In addition, whether cholangitis occurred in infants during the first month of operation was divided into cholangitis group and non-cholangitis group to investigate the changes of liver elastic modulus in the two groups before and after surgery in January. Results There was a statistically significant difference between the preoperative and postoperative liver elastic modulus values in the non-cholangitis group and the cholangitis group respectively（P<0.05）. The liver elastic modulus of cholangitis group was significantly higher than that of the non-cholangitis group in January after surgery（P=0.001）. The preoperative liver elastic modulus values of all infants showed a linear relationship with the age of the day(R=0.258，P=0.000), and the greater the age, the greater the elastic modulus. However, there was no significant linear correlation between the daily age and the liver elastic modulus in January（P=0.055）. Conclusion Ultrasonic real time shear elastic imaging(SWE) technique has certain value in the detection of liver stiffness in infants with biliary atresia and the changes of liver stiffness after surgery in early cholangitis. |
| Key words: Biliary atresia Infant Shear wave elastography |
