| 摘要: |
| 应用血流向量成像（VFM）技术分析慢性肾脏病（慢性肾脏病） 患者左室能量损耗（EL）变化，探讨其定量评估慢性肾脏病患者左室功能受损的临床价值。方法 选取慢性肾脏病患者61例，其中左室射血分数（LVEF）≥50% 42例（A组），LVEF＜50% 19例（B组），另收集38例健康成人为正常对照组。应用VFM技术获取并计算充盈早期、左房收缩期、等容收缩期及射血期平均EL（E-EL-ave、A-EL-ave、I-EL-ave及Ej-EL-ave）。比较各组上述参数的差异，绘制受试者工作特征曲线分析其诊断不同程度左室功能受损的诊断效能，分析各个时相EL与常规超声参数的相关性。结果 与正常对照组比较，A组各个时相的EL均升高，B组A-EL-ave升高，Ej-EL-ave降低，差异均有统计学意义（均P＜0.05）。Ej-EL-ave在正常对照组、A组、B组表现出双相变化趋向。 Ej-EL-ave对慢性肾脏病患者早期左室功能受损及LVEF＜50%具有良好诊断效能（曲线下面积分别为0.907、0.861，均P＜0.001）。慢性肾脏病患者Ej-EL-ave与LVEF呈正相关（r=0.636，P＜0.01）。结论 VFM技术所测参数Ej-EL-ave可以作为评估慢性肾脏病患者左室泵功能效率的潜在新指标，有一定的临床应用价值。 |
| 关键词: 左室功能，能量损耗，慢性肾脏病 |
| DOI： |
| 投稿时间：2020-06-14修订日期：2021-02-27 |
| 基金项目:河北省卫生健康委青年科技课题 |
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| Quantitative Assessment of left ventricular function in patients with chronic kidney diseases by Vector Flow Mapping |
| wei wang,Wang Yue heng,Bai Hui,zhou Jin ling,Chang Qing |
| (The Second Hospital of He bei Medical University) |
| Abstract: |
| Quantitative Assessment of left ventricular function in patients with chronic kidney diseases by Vector Flow Mapping
WANG Wei，BAI Hui，ZHOU Jinling，CHANG Qing，WANG Yueheng
Department of Cardiac Ultrasound，The Second Hospital of He bei Medical University，Shijiazhuang 050000，China
ABSTRACT Objective To analyze the change characteristics of left ventricular energy loss（EL） in chronic kidney diseases by vector flow mapping（VFM）technique and explore the clinical value of EL in quantitative evaluating left ventricular function in patients with CKDchronic kidney diease.Methods Sixty-one CKD chronic kidney diease patients were selected in this study，including 42 patients with LVEF≥50% in group A，19 patients with LVEF＜50% in group B，Thirty-eight healthy adults were enrolled as normal control group. VFM analysis was executed to acquire and calculate left ventricle average EL during early filling phase（E-EL-ave），atrial filling phase（A-EL-ave），isovolumic contraction period（I-EL-ave），and ejection phase（Ej-EL-ave），the differences of above parameters in each group were compared. Receiver operating characteristic curve was drawn to analyze the diagnostic efficacy of different degrees of left ventricular dysfunction. Then the relationship between each phases EL and conventional ultrasound parameters were analyzed. Results 1.Compared with the normal control group，EL in all phases of group A were increased. A-EL-ave increased in group B，and Ej-EL-ave was to reduce. The differences were statistically significant（P＜0.05）. the control group to group B，Ej-EL-ave showed a biphasic trend in the control group , group A and group B. .Ej-EL-ave has good diagnostic efficacy for early left ventricular function impairment and LVEF＜50% in patients with CKD（AUC=0.907，0.861，respectively，P＜0.001） 2.Ej-EL-ave were strongly associated with LVEF in the patients with chronic kidney diease（r=0.636，P＜0.01）.Conclusion The parameter Ej-EL-ave measured by VFM technique can be used as a potential new indicator to evaluate the efficiency of left ventricular pump function in chronic kidney disease patients, which has certain clinical application value. |
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