摘要: |
目的 探讨正常乳腺组织与病变组织灰度比在乳腺病变鉴别诊断中的价值。方法 研究对象为在我院穿刺活检的患者328例,共337个病灶,其中良性183个,恶性154个。灰度比测量方法:采用Adobe Photoshop图像处理软件的“直方图”功能计算病灶和周围组织的灰度比。结果 1、良恶性病灶与周围组织的灰度比分别为:恶性组0.30±0.16;良性组0.47±0.18,两组具有统计学差异(p<0.05)。2、当鉴别诊断阈值设为0.335时,灰度比鉴别诊断恶性病变的敏感性为77.6%、特异性63.6%、曲线下面积为0.777。结论 灰度比在乳腺病变鉴别诊断中具有一定的价值。 |
关键词: 超声 二维 灰阶 比值 乳腺 |
DOI: |
投稿时间:2020-06-19修订日期:2020-06-19 |
基金项目: |
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The value of gray-level ratio in differentiating between malignant and benign breast lesionsLI Zhencai,PENG Kun |
Lizhencai,Peng kun |
(The Fourth Medical Center,Chinese PLA General Hospital) |
Abstract: |
ABSTRACT Objective To discuss the value of gray-level ratio in differentiating between malignant and benign breast lesions. Methods The research included 328 patients(337 nodules) with biopsy in our department. Among all the nodules,183 were benign and 154 were malignant. The gray-level ratio had been calculated using the histogram of the Adobe Photoshop software. Result The mean value of the malignant lesions(0.30±0.16) was statistically lower than that of the benign lesions(0.47±0.18,)(p<0.05). According to the ROC curve, the ratio cutoff value differentiating malignant from benign lesions was estimated to be 0.335. At this cutoff value, the ratio can predict malignancy with a sensitivity of 77.6%,specificity of 63.6%,yielding an area under the curve of 0.777. Conclusion Gray-level ratio has the potential to aid in the classification of benign and malignant breast lesions. |
Key words: Ultrasonography Two-dimensional Gray-level Ratio Breast |