ABSTRACT Objective To explore the ultrasound manifestations and prognosis of fetal ductus venosus abnormalities in early pregnancy.Methods : Retrospective review of 26 fetuses with ductus venosus abnormalities diagnosed by ultrasonography during early pregnancy in our hospital . Ductus venosus structure ,umbilical vein connection ,and fetal outcomes were recorded. Results 26 cases were found with absence of ductus venosus, In 4 cases of umbilical vein connected to the inferior vena cava, 2 cases of umbilical vein connected to the right atrium, 1 case of umbilical vein connected to the left atrium, 3 cases of portal-hepatic vein shunt, 16 cases of umbilical vein connected to the portal vein . The absence of ductus venosus showed that there was no ductus venosus entering the inferior phrenic vestibule in each section of the upper abdomen, the sequential connection of the umbilical vein-left portal vein-ductus venosus -inferior vena cava disappeared, and the umbilical vein bypassed the liver to form extrahepatic ectopic connection or intrahepatic shunt.7 cases had intracardiac and extracardiac abnormalities, 8 cases had extracardiac abnormalities , 2 cases had intracardiac abnormalities，9 cases without other structural abnormalities. 1 case of 18 trisomy syndrome, 1case of 21 trisomy syndrome.14 cases of induced labor, and 9 cases showed no abnormality after birth, 1 case underwent repair of ventricular septal defect after birth, the growth and development was slow after operation, and 2 cases were lost to follow-up. Conclusions Most types of ductus venosus abnormalities can be diagnosed in early pregnancy, but it needs close follow-up and further diagnosis by ultrasound. The prognosis mainly depends on The prognosis mainly depends on malformations and chromosomal abnormalities.