| 摘要: |
| 目的：对比术前超声造影（CEUS）和超声内镜（EUS）在膀胱癌临床分期中的判别和评估价值。方法：选取2018年1月~2020年5月我院收入的膀胱癌患者97例，回顾并分析其病历资料，97例研究对象术前均行CEUS和EUS检查，术后均经病理诊断与分期；将患者病理分期结果作为金标准，对比CEUS和EUS在97例研究对象分期诊断中的符合率，对比两种检查方法在膀胱癌分期中诊断价值。结果：97例研究患者病理分期结果中，T1、T2、T3、T4期病例数分别是27、23、30、17例；CEUS在四期诊断中的符合率依次是77.78%、86.96%、56.67%、88.24%，EUS的诊断符合率分别是74.07%、65.22%、36.67%、35.29%，两种检查方法在T1、T2、T3三种分期中的诊断符合率对比无明显差异（P>0.05）；CEUS在T4期中的诊断符合率明显比EUS更高（P<0.05）。T4期膀胱癌诊断中，CEUS诊断灵敏度、特异度、阳/阴性预测值分别是87.50%、82.35%、58.33%、95.89%，EUS该四项诊断指标依次为67.50%、64.71%、29.73%、90.00%；ROC曲线中，CEUS诊断T4期膀胱癌AUC达0.849，EUS的AUC为0.661（均P<0.05），CEUS诊断T4期膀胱癌患者的灵敏度、特异度、阳阴性预测值、AUC均比EUS更高。结论：术前CEUS和EUS检查均可用于膀胱癌分期的诊断，但CEUS在T4期患者中的诊断价值比EUS检查要高。 |
| 关键词: 超声造影 超声内镜 膀胱癌 临床分期 |
| DOI： |
| 投稿时间：2020-06-23修订日期：2020-07-01 |
| 基金项目: |
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| A comparative study of the diagnostic value of contrast-enhanced ultrasonography and endoscopic ultrasonography in the clinical staging of bladder cancer |
| Shen Yeqin,Du Lei,Luo Ji,Wang Wensheng |
| () |
| Abstract: |
| Objective: To discriminative and evaluation of specific preoperative contrast-enhanced ultrasound (CEUS) and endoscopic ultrasonography (EUS) in clinical staging of bladder cancer. Methods: We selected 97 patients with bladder cancer who were admitted to our hospital from January 2018 to May 2020, reviewed and analyzed their medical records .97 patients underwent CEUS and EUS examination before operation. The results of pathological staging were used as gold standard to compare the coincidence rate of CEUS and EUS in the staging diagnosis of 97 subjects, and to compare the diagnostic value of the two methods for bladder cancer staging. Results: Among 97 patients with pathological stage, the number of cases in T1、T2、T3、T4 stage was 27,23,30 and 17 respectively.The coincidence rate of CEUS in the fourth stage diagnosis was 77.78%,86.96%,56.67%,88.24%, and the EUS diagnostic coincidence rate was 74.07%,65.22%,36.67%,35.29%, respectively, comparison of diagnostic coincidence rates between the two methods in T1、T2、T3 three stages showed no significant difference (P>0.05). The diagnostic coincidence rate of CEUS in T4 period is obviously higher than that of EUS (P<0.05). The CEUS diagnostic sensitivity, specificity, positive/negative predictive values were 87.50%,82.35%,58.33%,95.89%, respectively, EUS the four diagnostic indexes were 67.50%,64.71%,29.73%,90.00% (P<0.05), the AUC of CEUS diagnosis of T4 stage bladder cancer was 0.849 and the AUC of EUS was 0.661 in the curve(both P<0.05), the sensitivity, specificity, positive negative predictive value, and AUC of patients with stage T4 bladder cancer were higher than those of EUS. Conclusion: Preoperative CEUS and EUS examination can be used in the diagnosis of bladder cancer staging, but the diagnostic value of CEUS in patients with T4 stage is higher than that of EUS examination. |
| Key words: Contrast-enhance Ultrasound Endoscopic Ultrasonography Bladder cancer Clinical staging |
