brain injury is the main cause of neonatal adverse neurodevelopmental outcomes. Early diagnosis and treatment are of great importance for reducing neonatal mortality and disability and improving prognosis.Since the introduction of cranial ultrasound, it has proved to be an important diagnostic tool for evaluating neonatal brain morphology. Compared with CT and MRI, cranial ultrasound is more convenient, without radiation exposure or sedation, especially suitable for children with severe diseases. This paper reviews the application of cranial ultrasound and its new technology in common brain injury in neonates.