| 摘要: |
| 目的 运用实时剪切波弹性成像（SWE）技术初步建立健康成人视神经硬度的参考范围，并探索与其相关的影响因素。
方法 选取210例健康成人作为研究对象，运用SWE定量视神经硬度范围，分析性别、年龄、体质指数（BMI）、视神经鞘直径与视神经平均弹性值(Emean)之间的相关性；所有受检者按年龄分为三个亚组：a组：18-37岁(70例)；b组：38-57岁(70例)；c组：58-78岁(70例)，比较各亚组间基线资料、视神经鞘直径及Emean值的差异性。
结果 健康成人视神经Emean值的范围约10.37±1.56kPa，男、女性视神经Emean值差异无统计学意义(P＞0.05),左、右侧视神经Emean值差异无统计学意义（P＞0.05）；各亚组间视神经Emean值差异均有统计学意义（P＜0.001）。相关性分析表明：年龄与视神经Emean值呈明显正相关，且随着年龄增加，a、b、c组Emean值有逐渐升高的趋势。
结论 剪切波弹性成像可定量评估视神经硬度，为各种原发或继发性视神经病变提供参考依据。 |
| 关键词: 剪切波弹性成像 视神经 健康成人 |
| DOI： |
| 投稿时间：2020-07-02修订日期：2020-08-06 |
| 基金项目: |
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| Application of shear wave elastography in the evaluation of optic nerve stiffness in healthy adults |
| Wang Dan Dan,Qin Qin,Li Rui,Tong Ming Hui |
| () |
| Abstract: |
| Objective Using real-time shear wave elastography (SWE) to initially establish the reference range of the optic nerve stiffness in healthy adults, and explore the related influencing factors.
Methods 210 healthy adults were selected as the research objects and SWE was used to quantify the optic nerve stiffness range. The correlation between gender, age, body mass index (BMI), optic nerve sheath diameter and mean optic nerve elasticity (Emean) was analyzed. All the subjects were divided into three subgroups by age: Group a: 18-37 years old (70 cases); Group b: 38-57 years old (70 cases); Group c: 58-78 years old (70 cases). The differences of baseline data, optic nerve sheath diameter and Emean value among subgroups were compared.
Results The Emean values of the optic nerve of healthy adults ranged from 10.37±1.56kpa, and the Emean values of the optic nerve of males and females showed no statistical significance (P＞0.05), while the Emean values of the left and right optic nerves showed no statistical significance (P > 0.05). The differences in the optic nerve Emean values among the subgroups were statistically significant (P < 0.001). Correlation analysis showed that age was positively correlated with the Emean value of optic nerve, and with the increase of age, the Emean value of groups a, b and c had a trend of gradual increase.
Conclusion Shear wave elastography can quantitatively evaluate the optic nerve stiffness and provide a reference basis for various primary or secondary optic neuropathy. |
| Key words: shear wave elastography optic nerve healthy adults |
