| 摘要: |
| 目的探讨应用剪切波弹性成像技术（SWE）评估米非司酮无痛人流术前宫颈软化效果的可行性。方法选取我院行无痛人流手术的孕妇87例，随机分成试验组43例和对照组44例。试验组术前1 d晚上8时服用米非司酮50mg，对照组不服用药物。应用SWE技术在术前1 d（试验组用药前）及手术当天分别测量宫颈外口前唇及后唇的剪切波速度（SWS），比较试验组及对照组两次所测SWS的差异，Spearman相关分析手术当天所测宫颈SWS与术中宫颈扩张程度评价的关系。结果试验组术前1 d测得的宫颈前唇及后唇SWS与手术当天测值比较，差异均有统计学意义（均P＜0.05）；对照组术前1 d测得的宫颈前唇及后唇SWS与手术当天测值比较，差异均无统计学意义。相关性分析结果显示，手术当天所测的宫颈前唇SWS与术中宫颈扩张程度评价标准呈正相关（ρ=0.458，P＜0.05），宫颈后唇SWS与术中宫颈扩张程度无明显相关性（ρ=0.177）。结论应用SWE可检测米非司酮引起的宫颈软化效果，宫颈外口前唇SWS有望作为客观评估宫颈软硬度的指标之一。 |
| 关键词: 剪切波弹性成像 米非司酮 无痛人流手术 宫颈 |
| DOI： |
| 投稿时间：2020-07-12修订日期：2021-03-01 |
| 基金项目:九院融合基金 |
|
| Evaluation of the cervical softening effect of mifepristone using shear wave elastography |
| wangfeinan,xiongping |
| (Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine) |
| Abstract: |
| Objectve To explore the feasibility of applying shear wave elastography (SWE） to evaluate the effect of mifepristone on cervical softening before painless abortion surgery. Methods A total of 87 pregnant women who underwent painless abortion surgery in our hospital were selected and randomly divided into a test group of 43 cases and a control group of 44 cases. The test group took 50 mg of mifepristone at 8 pm the day before surgery，while the control group took no medication. The SWE technique was used to measure the shear wave speed （SWS） of the external os anterior and posterior on the day before the surgery （before the medication of the test group） and the day of the surgery. The difference between the two SWS measured in the test group and the control group was compared，Spearman correlated and the relationship between the cervical SWS measured on the day of surgery and the intraoperative cervical dilation evaluation was analyzed. Results The SWS of the anterior lip and posterior lip of the cervix measured one day before the surgery in the test group were statistically different from those measured on the day of the surgery（P＜0.05）. There was no statistic difference between the SWS of the anterior lip and posterior lip of the cervix measured one day before the surgery and the value measured on the day of the surgery in the control group. The results of correlation analysis showed that the SWS of the anterior cervix lip on the day of surgery was positively correlated with the intraoperative cervical dilation evaluation（ρ=0.458，P＜0.05）.There was no significant correlation between the SWS of the posterior cervix lip and the intraoperative cervical dilation evaluation （ρ=0.177）.Conclusion SWE can be used to detect the cervical softening effect caused by mifepristone. The SWS of the external os anterior is expected to be one of the indicators for objectively evaluating cervical softness. |
| Key words: Shear wave elastography Mifepristone Painless abortion surgery Cervix |
