Objective To investigate speckle tracking imaging and right heart contrast-enhanced echocadiography in predicting the recurrence of paroxysmal atrial fibrillation（PAF）.Methods A total of 33 patients who were diagnosed with PAF in the cardiovascular medicine department from January 2019 to December 2019 were prospective study. 2D echocardiography and right heart contrast-enhanced echocardiography were performed at AF paroxysm and sinus rhythm respectively. Right ventricular end diastolic area, right ventricular end systolic area, right ventricular fractional area change (FAC) was measured with and without contrast-enhanced echocardiography respectively. The changes of the endocardial boundary of the right ventricle were observed during contrast-enhanced echocardiography. Tricuspid annular plane systolic excursion (TAPSE), left ventricular global longitudinal strain (LVGLS)，right ventricular global longitudinal strain (RVGLS) were calculated at atrial fibrillation paroxysm and sinus rhythm respectively. The values which were measured at sinus rhythm and with contrast-enhanced echocardiography were taken as the baseline value. After 6 months, the two groups were divided according to whether atrial fibrillation recurred or not. The parameters were evaluated again. Compared to the differences between these groups. Results There was statistical difference between patients with and without contrast-enhanced echocardiography of FAC, when the value of improvement was≥6. LVGLS, RVGLS decreased in AF paroxysm than those in sinus rhythm (P<0.05). After 6 months, RVGLS in the recurrent group decreased from the baseline value of the same group (P<0.05), and was lower than that in the non-recurrent group(P<0.05). The baseline value of RVGLS in the recurrence group was lower than that in the non-recurrence group (P<0.05). There was no significant difference in the value of LVGLS between these groups. When RVGLS<17.98, sensitivity and specificity to predict AF recurrence was 71.1% and 72.9%. Conclusions RVGLS can be sensitive to changes in right ventricular function, which could help to predict PAF recurrence. However, LVGLS has no predictive value for PAF recurrence. Contrast enhancement of the right heart can significantly improve the clarity of right ventricular images, but has no significant effect on the prediction of PAF recurrence.