| 摘要: |
| 目的：探讨超声检查在特发性性早熟女童鉴别诊断及真性性早熟女童疗效评估中的应用价值。方法：将我院2016年6月-2019年5月收治的86例特发性性早熟女童纳入研究,根据促性腺激素释放激素(GnRH)激发实验结果将所有患儿分成真性组(中枢性性早熟)52例及与假性组(外周性性早熟)34例,另取同期30例健康女童作为对照组。比较三组子宫以及卵巢超声检查结果。此外,真性组女童采用促性腺激素释放激素类似物(GnRHa)治疗,比较治疗前与治疗8个月后子宫以及卵巢超声检查结果。结果：真性组卵巢长径、卵巢横径、卵巢前后径以及最大卵泡直径均大于假性组与对照组(均P＜0.05)；而假性组与对照组上述各项指标水平对比均无统计学差异(均P＞0.05)。真性组子宫长径、子宫横径、子宫前后径均大于假性组与对照组,且假性组上述指标均大于对照组(均P＜0.05)。真性组治疗后卵巢长径、卵巢横径、卵巢前后径以及最大卵泡直径小于治疗前(均P＜0.05)。真性组治疗后子宫长径、子宫横径、子宫前后径均小于治疗前(均P＜0.05)。结论：超声检查下特发性性早熟女童的子宫和卵巢均存在明显增大,且在真性性早熟女童中此特征更加明显,其可辅助评估真性性早熟女童的治疗效果。 |
| 关键词: 特发性性早熟 诊断 超声 疗效评估 |
| DOI： |
| 投稿时间：2020-09-15修订日期：2020-09-27 |
| 基金项目:四川省医学会科研课题计划(Q161042) |
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| Analysis of the application value of ultrasonography in the differential diagnosis of idiopathic precocious puberty and the evaluation of curative effect of true precocious puberty in girlsYu jia1, Zeng Xue-lian2, Zhang Zong-hua3, Liu Wei-ying1, Liu Ping1 |
| Yu jia,Zeng Xue-lian,Zhang Zong-hua,Liu Wei-ying |
| () |
| Abstract: |
| Objective: To explore the application value of ultrasound in the differential diagnosis of idiopathic precocious puberty and the evaluation of curative effect of true precocious puberty in girls. Methods: 86 cases of girls with idiopathic precocious puberty who were admitted to our hospital from June 2016 to May 2019 were included in the study. According to the results of the gonadotropin-releasing hormone (GnRH) stimulation experiment, all the children were divided into the 52 cases with the true group (central precocity) and 34 cases with the sham group (peripheral precocity), and 30 healthy girls in the same period were selected as the control group. The results of uterine and ovarian ultrasound examination were compared in the three groups. In addition, the girls in the true group were treated with gonadotropin-releasing hormone analogue (GnRHa), and the results of uterine and ovarian ultrasound examination were compared before and 8 months after treatment. Results: The length diameter, transverse diameter, anteroposterior diameter and maximum follicular diameter of the true group were all larger than those of the sham group and the control group (all P<0.05). There was no statistical difference of the above indicators levels between the sham group and the control group (all P＞0.05). The length diameter, transverse diameter and anteroposterior diameter of the true group were all greater than those of the sham group and the control group, and the above indicators of the sham group were all greater than those of the control group (all P<0.05). After treatment, the length diameter, transverse diameter, anteroposteric diameter and maximum follicular diameter of the ovary in the true group were smaller than those before treatment (all P<0.05). After treatment, the length diameter, transverse diameter and anteroposterior diameter of the uterus of the true group were all smaller than those before treatment (all P< 0.05). Conclusion: Under ultrasound examination, the uterus and ovaries of idiopathic precocious puberty girls are significantly enlarged, and this feature is more obvious in true precocious puberty girls, which can assist to evaluate the therapeutic effect of true precocious puberty girls. |
| Key words: Idiopathic precocity Diagnosis Ultrasound Curative effect evaluation |
