Objective: To investigate the causes of thrombosis after renal transplantation and the value of early diagnosis of ultrasound imaging; retrospectively analyze a case of pulmonary embolism caused by a huge right ventricular thrombosis 10 years after renal transplantation: Conclusion: Previous studies have shown that thrombosis most commonly occurs after transplantation6 Within months, but under the action of various risk factors such as hypertension, overweight, renal insufficiency, there is still a long-term risk of thrombosis. Clinically, it is necessary to strengthen evaluation, prevent first, and treat in time; cardiac ultrasound imaging can accurately find the heart cavity Internal thrombotic lesions, combined with lower extremity vascular ultrasound, win the opportunity for the early diagnosis of pulmonary embolism, and the antithrombotic treatment has a significant effect.