胎儿肝内门静脉-体静脉异常连接的产前超声诊断
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青岛市妇女儿童医院

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Prenatal sonographic diagnosis of fetal intrahepatic portosystemic shunt
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Women and Children’s Hospital of Qingdao

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    目的 探讨胎儿肝内门静脉-体静脉异常连接的产前超声诊断价值。资料与方法 回顾分析17例胎儿肝内门静脉-体静脉异常连接的产前超声诊断特征,结合临床资料及追踪随访出生进展状况。结果 Park分型:Ⅰ型0例,Ⅱ型14例(82.35%),Ⅲ型2例(11.77%),Ⅳ型1例(5.88%)。1例合并食道闭锁和静脉导管缺失,1例合并双肾发育不良和双足姿势异常,2例合并静脉导管缺失,1例合并迷走右锁骨下动脉,其余均未见其他合并畸形。1例出现宫内发育迟缓,1例出现心功能不全,其余均未见其他并发症。妊娠结局:2例终止妊娠,1例宫内死亡,14例自然分娩(其中1例异常分流宫内自发闭合)。随访时间6~36个月,9例生后异常分流自发闭合,2例行介入栓塞治疗,1例分流仍持续性存在,1例失访。结论 产前超声对胎儿肝内门静脉-体静脉异常连接具有较高诊断准确性,为出生后临床干预提供重要参考信息。

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    Objective To evaluate the value of prenatal sonographic diagnosis of fetal intrahepatic portosystemic shunt. Materials and Methods The prenatal ultrasonographic features of 17 cases with intrahepatic portosystemic shunt were analyzed retrospectively. Combining with clinical data and following-up the birth progress. Results Park type: Type Ⅰ 0 case, Type Ⅱ 14 cases (82.35%), Type Ⅲ 2 cases (11.77%), Type Ⅳ 1 case (5.88%). 1 case had comorbidity with esophageal atresia and absent ductus venosus, 1 case with bilateral kidney dysplasia and abnormal bipedal posture, 2 cases with absent ductus venosus, 1 case with aberrant right subclavicular artery, others were not seen comorbidity. 1 case was complicated with intrauterine growth retardation, 1 case with cardiac insufficiency, the rest were not seen other complications. Pregnancy outcome: 2 cases with termination of pregnancy, 1 case with intrauterine death, 14 cases with natural delivery (1 case with intrauterine spontaneous closure of the shunt was included ). During follow-up period of 6-36 months postnatally, 9 cases of abnormal shunt closed spontaneously, 2 cases underwent interventional embolization, 1 case was still persistent with the shunt and 1 case was lost to follow-up. Conclusion Prenatal ultrasonography has high diagnostic accuracy for fetal intrahepatic portosystemic shunt and provides important reference information for clinical intervention after birth.

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孙永杰.胎儿肝内门静脉-体静脉异常连接的产前超声诊断[J].临床超声医学杂志,2021,23(11):

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  • 收稿日期:2020-11-15
  • 最后修改日期:2020-12-13
  • 录用日期:2020-12-18
  • 在线发布日期: 2021-11-29
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