Objective To summarize the characteristics of esophageal atresia sonography and evaluate the accuracy of prenatal ultrasound in the diagnosis of esophageal atresia, so as to improve the prenatal detection rate. Methods sixteen fetuses with esophageal atresia diagnosed by prenatal ultrasound in Anhui Women and Child Health Care Hospital from November 2016 to September 2020 were summarized and their follow-up results were analyzed to analyze their characteristic ultrasonic manifestations. Results Prenatal ultrasound manifestations of 16 fetuses with esophageal atresia were proposed:8 cases non-visualization gastric bubble and 5 cases showed small gastric bubble. There were 7 cases of Polyhydramnios and 3 cases of amniotic fluid more. 11 cases of small abdominal circumference. 10 were shown with the dilated proximal esophageal pouch. When the fetuses swallowed, esophageal pouch was changed to be small until it disappeared.It was confirmed that 6 cases were esophageal atresia and 4 cases were esophageal atresia with tracheoesophageal fistula, with sensitivity (62.5%) and specificity (100%). Induction of labor in 13 of the 16 cases; Three cases were born successfully, of which 2 were operated on and 1 was normal. 2 cases were misdiagnosed by ultrasound (1 case induced labor), and the accuracy rate of ultrasonic diagnosis of esophageal atresia was 87.5%..Conclusion: Fetal EA has the characteristic ultrasonographic appearances． Prenatal sonography may be of important value in the diagnosis of fetal esophageal atresia．