| 摘要: |
| 摘要
目的：对比绝经前和绝经后三阴性乳腺（Triple negative breast cancer，TNBC）患者的超声和临床病理特征的差异。
方法：选取我院经手术病理证实为TNBC的66例患者，其中40例绝经前女性（绝经前组）和26例绝经后女性（绝经后组）。回顾性收集及对比分析两组的超声及临床病理特征。
结果：两组间在肿瘤直径、肿瘤位置、组织学等级和Ki-67表达、腋窝淋巴结转移的差异没有统计学意义（P均＞0.05）。两组间在肿瘤形态、生长方式、边缘、血流分级及BI-RADS分类方面差异有统计学意义（P均＜0.05）。两组间在肿瘤边界、微钙化、内部回声、后方回声的差异没有统计学意义（P均＞0.05）。与绝经后组TNBC比较，绝经前组TNBC更多表现为形态规则、水平生长、边缘微分叶、血流Adler 3级以及BI-RADS分级归为3-4类。
结论：绝经前和绝经后患者TNBC有一定显著差异的超声特征，为超声鉴别诊断TNBC提供更多依据。 |
| 关键词: 三阴性乳腺癌 绝经 超声检查 |
| DOI： |
| 投稿时间：2020-11-30修订日期：2020-11-30 |
| 基金项目: |
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| Comparative study of ultrasound characteristics of triple-negative breast cancer before and after menopause |
| zhuping,liang xi |
| () |
| Abstract: |
| Summary Purpose: To compare the differences in ultrasound and clinicopathological characteristics of triple negative breast cancer (TNBC) patients before and after menopause.Methods: We selected 66 patients with TNBC confirmed by surgery and pathology in our hospital, including 40 premenopausal women (premenopausal group) and 26 postmenopausal women (postmenopausal group). The ultrasound and clinicopathological characteristics of the two groups were retrospectively collected and compared.Results: There were no significant differences in tumor diameter, tumor location, histological grade, Ki-67 expression, and axillary lymph node metastasis between the two groups (all P>0.05). There were statistically significant differences between the two groups in terms of tumor morphology, growth pattern, margin, blood flow grade and BI-RADS classification (P<0.05). There was no significant difference between the two groups in tumor boundary, microcalcification, internal echo, and posterior echo (P>0.05). Compared with the postmenopausal group TNBC, the premenopausal group TNBC showed more regular morphology, horizontal growth, marginal differential lobes, blood flow Adler level 3, and BI-RADS classification into 3-4 categories.Conclusion: Premenopausal and postmenopausal patients with TNBC have some significant differences in ultrasound characteristics, which provide more evidence for the differential diagnosis of TNBC by ultrasound. |
| Key words: Triple negative breast cancer menopause ultrasonography |
