| 摘要: |
| 摘 要 目的 探讨盆腔超声单指标及多指标联合对中枢性性早熟（Central Precocious Puberty，CPP）的诊断价值。方法 CPP女童205例为CPP组，另选同期体检的健康女童221例为对照组，行盆腔超声检查比较两组子宫、卵巢各指标的大小；选取曲线下面积（Area under curve，AUC）值高的超声指标建立二元Logistic回归模型，得联合超声指标Y，比较单指标与联合指标的AUC值。 结果 CPP组子宫体积、卵巢体积、较大卵泡直径、卵泡个数、内膜厚度均较对照组不同程度增大，两组比较差异有统计学意义（P＜0.05）。ROC曲线结果显示，卵巢体积诊断CPP的AUC为0.82 ml，截断值为1.16 ml，对应的特异性72.50%，敏感性82.20%；子宫体积诊断CPP的AUC为0.79 ml，截断为1.66 ml，对应的特异性71.30%，敏感性61.20%。联合子宫体积、卵巢体积和内膜厚度形成的联合超声指标Y对中枢性性早熟的诊断价值大于单个超声指标（P＜0.05），其AUC为0.97， 截断值为0.90，特异性97.20%，敏感性85.19%。 结论 联合超声指标能进一步提高盆腔超声对中枢性性早熟患儿的诊断准确率，有重要的临床应用价值。 |
| 关键词: 超声检查 中枢性性早熟 儿童 |
| DOI： |
| 投稿时间：2020-12-28修订日期：2021-09-01 |
| 基金项目:雅安地区女性生殖健康及胎儿出生缺陷的医学防治 |
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| Diagnostic value of combined ultrasound index in central precocious puberty |
| yuan xiaohan,cha xiaoxia,he lihong,liu yun,xiang xingyue |
| () |
| Abstract: |
| ABSTRACT Objective To explore the diagnostic value of pelvic ultrasound with single index and combined index for central precocious puberty.Methods 205 CPP girls were in the CPP group, and 221 healthy girls who underwent physical examination during the same period were selected as the control group. Perform pelvic ultrasound examination to compare the sizes of the uterus and ovaries of the two groups; select the high area under the curve (AUC) value and independent ultrasound index to establish a binary logistic regression model to obtain the combined ultrasound index Y, and compare the AUC values of the single index and the combined index. Results The uterine volume, ovarian volume, larger follicle diameter, number of follicles, and endometrial thickness in the CPP group were all increased to different degrees than those in the control group. The difference between the two groups was statistically significant (P<0.05). The ROC curve results showed that the AUC for the diagnosis of CPP by ovarian volume was 0.82 ml, cut-off value was 1.16 ml, specificity was 72.50%, and sensitivity was 82.20%; the AUC for the diagnosis of CPP by uterine volume was 0.79 ml, cut-off was 1.66 ml, specificity is 71.30%, and sensitivity is 61.20%. The combined ultrasound index Y combined with the formation of uterine volume, ovarian volume and endometrial thickness is more valuable in the diagnosis of central precocious puberty than a single ultrasound index (P＜0.05), with an AUC of 0.97, a cut-off value of 0.90, a specificity of 97.20%, a sensitivity of 85.19%. Conclusions The combined ultrasound index can further improve the diagnostic accuracy of pelvic ultrasound in children with central precocious puberty.
KEYWORDS Pelvic ultrasound；Central precocious puberty；Logistic Regression |
| Key words: Pelvic ultrasound Central precocious puberty Logistic Regression |
