| 摘要: |
| 目的 探讨化生性乳腺癌(metaplastic breast carcinoma,MPBC)的临床病理及超声特点，并与同期随机的非特殊类型浸润性癌（invasive ductal breast carcinoma of no special type,IDC-NOS）进行鉴别诊断。方法 回顾性分析2015年1月～2020年12月在我院经手术病理证实的33例MPBC及66例IDC-NOS的临床病理和超声特征。结果 MPBC最常见的超声表现如下：低回声肿块、边缘模糊、形态不规则、Adler II～III级、后方回声增强。MPBC的腋窝淋巴结转移率低于IDC-NOS。鳞状细胞癌是MPBC的常见病理类型，三阴型是其主要的病理分子分型。MPBC的Ki-67的平均值（59.4%）高于IDC-NOS（37.5%）。在临床表现方面，MPBC与IDC-NOS间无统计学意义（P>0.05）。结论 MPBC可表现出不同于IDC-NOS的临床病理学及超声特点。 |
| 关键词: 乳腺癌 化生癌 浸润性癌 超声；病理 |
| DOI： |
| 投稿时间：2021-01-27修订日期：2021-03-01 |
| 基金项目:微波消融治疗乳腺癌原发灶诱导NK细胞抑制远处转移灶的机制研究 |
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| The differentiation of metaplastic breast carcinoma and invasive ductal breast carcinoma of no special type in clinicopathological and ultrasonographic characteristics |
| GONG Haiyan,DU Liwen,LI Cuiying,WANG Hui,DENG Jing,ZHOU Wenbin |
| (1Department of Ultrasound,2 Department of Breast surgery,the First Affliated Hospital of NJMU) |
| Abstract: |
| Objective The aim of this study was to investigate the clinicopathological and ultrasonographic characteristics of metaplastic breast carcinoma（MPBC）and differential diagnosis from invasive ductal breast carcinoma of no special type (IDC-NOS) selected at the same time randomly. Methods We retrospectively reviewed the clinicopathological and ultrasonographic characteristics of 33 patients with MPBC and 66 patients with IDC-NOS confirmed by pathology in our hospital from January 2015 to December 2020. Results The most common features of MPBC observed in ultrasound were as follows:hypoechoic mass,indistinct margin,irregular shape, Adler II～III,posterior acoustic enhancement.The rates of axillary nodal involvement were lower than that of IDC-NOS. Squamous cell carcinoma was the common pathological type of MPBC. Triple negative type was the main molecular subtype of pathology. The average score of Ki-67 （59.4%）was higher than that of IDC-NOS (37.5%).There were no significant differences in clinical manifestations (P>0.05). Conclusion Compared with IDC-NOS, MPBC can show the differential clinicopathological and ultrasonographic characteristics. |
| Key words: Breast carcinoma Metaplastic carcinoma Invasive carcinoma Ultrasonography Pathology |
