| 摘要: |
| 目的：探讨超声造影(CEUS)时间-强度曲线(TIC)与CT血管造影(CTA)对缺血性脑卒中(IS)复发的预测价值。方法：选取2018年1月～2020年1月我院收治的95例缺血性脑卒中患者,分别采用CEUS、CTA对所有患者检查。患者出院后随访1年。根据随访结果分为复发组与未复发组进行比较并采用ROC曲线评估预测价值。结果：复发组年龄≥65岁占比明显高于未复发组,合并高血压占比明显高于未复发组(P<0.05)；未复发组血管狭窄程度明显优于复发组(P<0.05)；复发组达峰时间(TTP)明显短于未复发组,峰值强度(PI)、曲线下面积(AUCTC)明显高于未复发组(P<0.05),Logistic回归分析结果显示,TTP短、血管狭窄、AUCTC高是IS复发的独立危险因素；ROC曲线分析显示,AUCTC、CTA、两项联合预测IS复发的AUC分别为0.694、0.906、0.951,其敏感度和特异度分别为81.8%、52.9%,81.8%、90.2%,88.6%、100%。结论：CEUS-TIC联合CTA对IS复发预测价值高于其单独预测,血管狭窄及不稳定斑块是IS复发危险因素。 |
| 关键词: 超声造影 时间强度曲线 CTA 缺血性脑卒中 复发 预测价值 |
| DOI： |
| 投稿时间：2021-02-26修订日期：2021-04-13 |
| 基金项目: |
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| Predictive value of time-intensity curve of contrast-enhanced ultrasound and CTA for recurrence of ischemic stroke |
| WANG HAOXIANG,YUANYUAN,LONG HAIBO,TENG ZHIPENG,WAN WENWU,WANG GUANG,PENG XING,CHEN FEI |
| () |
| Abstract: |
| Objective: To explore the predictive value of contrast-enhanced ultrasound (CEUS) time-intensity curve (TIC) and CT angiography (CTA) for recurrence of ischemic stroke (IS). Methods: A total of 95 patients with ischemic stroke admitted to our hospital from January 2018 to January 2020 were selected, and all patients were examined by CEUS and CTA. The patient was followed up for 1 year after discharge. According to the follow-up results, they were divided into recurrence group and non-recurrence group for comparison, and ROC curve was used to evaluate the predictive value. Results: The proportion of age ≥ 65 years in the recurrence group was significantly higher than that of the non-recurring group, and the proportion of combined hypertension was significantly higher than that of the non-recurring group (P<0.05); the degree of vascular stenosis in the non-recurring group was significantly better than that of the recurring group (P<0.05) The time to peak (TTP) of the recurrence group was significantly shorter than that of the non-recurring group, and the peak intensity (PI) and area under the curve (AUCTC) were significantly higher than those of the non-recurring group (P<0.05). Logistic regression analysis showed that the TTP was short and the blood vessel Stenosis and high AUCTC are independent risk factors for IS recurrence; ROC curve analysis shows that the AUC of AUCTC, CTA, and the two combined predictions for IS recurrence are 0.694, 0.906, and 0.951, respectively, and their sensitivity and specificity are 81.8% and 52.9%, respectively , 81.8%, 90.2%, 88.6%, 100%. Conclusion: The value of CEUS-TIC combined with CTA in predicting IS recurrence is higher than its independent prediction. Vascular stenosis and unstable plaque are risk factors for IS recurrence. |
| Key words: contrast-enhanced ultrasound time intensity curve CTA ischemic stroke recurrence predictive value |
