| 摘要: |
| 目的：应用二维斑点追踪技术分析正常人主动脉根部运动力学的特征。方法：将208例健康志愿者按年龄分为4组：A组：20~29岁,B组：30~39岁,C组：40~49岁,D组：50岁及以上。分析其主动脉窦及升主动脉管壁的纵向应变及曲线特点,比较纵向应变及应变率的差异以及其与年龄、左室整体纵向应变、每搏量指数以及血压的相关性。结果：正常成年人主动脉窦瓣环侧和窦管交界侧纵向应变曲线有明显差异,主动脉窦整体纵向应变及升主动脉整体纵向应变均随着年龄的增加而减小,且与年龄呈负相关(r＝-0.614、-0.507,P＜0.001),与LVGLS呈正相关(r＝0.487、0.313,P＜0.001),与SVI呈正相关(r＝0.321、0.336,P＜0.001)。主动脉窦LS及LSR与动脉血压之间无显著相关性。主动脉窦瓣环侧及窦管交界侧的收缩期LSR峰值与LVGLS呈正相关(r＝0.512、0.541,P＜0.001),但与SVI无明显相关性。主动脉窦及升主动脉前壁的LS值均小于后壁的LS值(P＜0.001)。结论：正常成人主动脉根部LS和LSR曲线波形具有节段性特征。主动脉根部前壁和后壁应变具有异质性。主动脉窦部LS峰值随年龄的增加而降低,且与SVI及LVGLS呈正相关。主动脉窦部LS及收缩期LSR体现了左心室-主动脉耦联关系。 |
| 关键词: 主动脉根部 纵向应变 二维斑点追踪 |
| DOI： |
| 投稿时间：2021-03-13修订日期：2021-03-13 |
| 基金项目:辽宁省自然科学基金面上项目(2019-MS-093) |
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| Longitudinal Mechanical Characteristics of Aortic Root in Normal Adults: a Two-dimensional Strain Study |
| peiyongkai,wujuan,wangyanli,gongmin,jijiamei,wujun |
| () |
| Abstract: |
| Objective Assess the mechanical motion characteristics of the aortic root in 208 healthy adult volunteers via 2D-STE. Methods The Valsalva sinus (VS) was subdivided into four segments for speckle tracking, namely the anterior aortic annular segment (AAA-VS), the posterior aortic annular segment (PAA-VS), the anterior sinotubular junction segment (ASJ-VS), and the posterior sinotubular junction segment (PSJ-VS). The longitudinal strain (LS) and the longitudinal strain rate (LSR) of different aortic root segments were assessed by 2D-STE. Results The LS waveforms of the AAA-VS and PAA-VS were markedly different from those of the ASJ-VS and PSJ-VS. The LS values of the VS and AAo were negatively correlated with age (r = -0.614, -0.507, P < 0.001), positively correlated with LVGLS (r = 0.487, 0.313, P < 0.001), and positively correlated with SVI (r = 0.321, 0.336, P < 0.001). There was no significant correlation between LS, peak systolic LSR values of aortic sinus and PP. The peak systolic LSR values of AA-VS and SJ-VS were positively correlated with LVGLS (r = 0.512, 0.541, P < 0.001), respectively, but had no significant correlation with SVI. Furthermore, the LS values of anterior wall of aortic sinus and ascending aorta were lower than those of posterior wall (P < 0.001). Conclusions The waveforms of the LS and LSR curves of the aortic root in normal adults had the segmental characteristics. The longitudinal mechanical deformations of the aortic root showed regional variations. The LS of the aortic root are correlated with age, SVI and LVGLS. In addition, The systolic peak LSR values was useful to the further assess in understanding the ventricular-arterial coupling relationship. |
| Key words: aortic root longitudinal strain two-dimensional speckle tracking |
